Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 84561
MIM: 611316
HGNC: 15595
Ensembl: ENSG00000221955
Variants:
dbSNP: 84561
ClinVar: 84561
TCGA: ENSG00000221955
COSMIC: SLC12A8
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164713366 | Tumor necrosis factor alpha (TNF-alpha) inhibitors | Chemical | ClinicalAnnotation | associated | PD | 26194362 | |
| PA445451 | Psoriasis | Disease | ClinicalAnnotation | associated | PD | 26194362 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37725242 | 2023 | SLC12A8 mediates TKI resistance in EGFR-mutant lung cancer via PDK1/AKT axis. | 0 |
| 37814877 | 2023 | [SLC12A8 promotes proliferation, invasiveness, migration and epithelial-mesenchymal transition of bladder cancer cells by activating JAK/STAT singaling]. | 0 |
| 37725242 | 2023 | SLC12A8 mediates TKI resistance in EGFR-mutant lung cancer via PDK1/AKT axis. | 0 |
| 37814877 | 2023 | [SLC12A8 promotes proliferation, invasiveness, migration and epithelial-mesenchymal transition of bladder cancer cells by activating JAK/STAT singaling]. | 0 |
| 34365894 | 2021 | Solute carrier family 12 member 8 (SLC12A8) is a potential biomarker and related to tumor immune cell infiltration in bladder cancer. | 8 |
| 34365894 | 2021 | Solute carrier family 12 member 8 (SLC12A8) is a potential biomarker and related to tumor immune cell infiltration in bladder cancer. | 8 |
| 23325410 | 2013 | Physiology of SLC12 transporters: lessons from inherited human genetic mutations and genetically engineered mouse knockouts. | 79 |
| 23325410 | 2013 | Physiology of SLC12 transporters: lessons from inherited human genetic mutations and genetically engineered mouse knockouts. | 79 |
| 19472210 | 2009 | Molecular characterization of a human cation-Cl- cotransporter (SLC12A8A, CCC9A) that promotes polyamine and amino acid transport. | 25 |
| 19472210 | 2009 | Molecular characterization of a human cation-Cl- cotransporter (SLC12A8A, CCC9A) that promotes polyamine and amino acid transport. | 25 |
| 16297188 | 2005 | Systematic linkage disequilibrium analysis of SLC12A8 at PSORS5 confirms a role in susceptibility to psoriasis vulgaris. | 8 |
| 16297188 | 2005 | Systematic linkage disequilibrium analysis of SLC12A8 at PSORS5 confirms a role in susceptibility to psoriasis vulgaris. | 8 |
| 16297188 | 2005 | Systematic linkage disequilibrium analysis of SLC12A8 at PSORS5 confirms a role in susceptibility to psoriasis vulgaris. | 8 |
| 16297188 | 2005 | Systematic linkage disequilibrium analysis of SLC12A8 at PSORS5 confirms a role in susceptibility to psoriasis vulgaris. | 8 |
| 11863360 | 2002 | Identification of a psoriasis susceptibility candidate gene by linkage disequilibrium mapping with a localized single nucleotide polymorphism map. | 19 |
Citation
Dessen P
SLC12A8 (solute carrier family 12 member 8)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54624/slc12a8-(solute-carrier-family-12-member-8)
