Identity
HGNC
LOCATION
3q22.1
LOCUSID
ALIAS
MATR1,OATP2A1,PGT,PHOAR2,SLC21A2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6578
MIM: 601460
HGNC: 10955
Ensembl: ENSG00000174640
Variants:
dbSNP: 6578
ClinVar: 6578
TCGA: ENSG00000174640
COSMIC: SLCO2A1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000174640 | ENST00000310926 | Q92959 |
| ENSG00000174640 | ENST00000481359 | F8W9W8 |
| ENSG00000174640 | ENST00000493729 | E7EU40 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164713347 | Thiazides, plain | Chemical | ClinicalAnnotation | associated | PD | 28783044 | |
| PA444534 | Hypernatremia | Disease | ClinicalAnnotation | associated | PD | 28783044 | |
| PA444552 | Hypertension | Disease | ClinicalAnnotation | associated | PD | 28783044 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37906648 | 2024 | Evaluation of ADRB2 and OATP2A1 genetic polymorphisms in Indian patients with primary open-angle glaucoma. | 0 |
| 37915296 | 2024 | Genotype and phenotype characterization of primary hypertrophic osteoarthropathy type 2 and chronic enteropathy associated with SLCO2A1: Report of two cases and literature review. | 1 |
| 37906648 | 2024 | Evaluation of ADRB2 and OATP2A1 genetic polymorphisms in Indian patients with primary open-angle glaucoma. | 0 |
| 37915296 | 2024 | Genotype and phenotype characterization of primary hypertrophic osteoarthropathy type 2 and chronic enteropathy associated with SLCO2A1: Report of two cases and literature review. | 1 |
| 36549465 | 2023 | Novel pathogenic variants in SLCO2A1 causing autosomal dominant primary hypertrophic osteoarthropathy. | 1 |
| 36706979 | 2023 | N-glycosylation modifies prostaglandin E(2) uptake by reducing cell surface expression of SLCO2A1. | 1 |
| 36731680 | 2023 | Elevated PGT promotes proliferation and inhibits cell apoptosis in preeclampsia by Erk signaling pathway. | 1 |
| 36907595 | 2023 | A Novel Chronic Enteropathy Associated with SLCO2A1 Gene Mutation: Enterography Findings in a Multicenter Korean Registry. | 1 |
| 37327083 | 2023 | Attenuated Expression of SLCO2A1 Caused by DNA Methylation in Pediatric Inflammatory Bowel Disease. | 0 |
| 37861627 | 2023 | Identification of three novel mutations in SLCO2A1 in Asian-Indians with Pachydermoperiostosis. | 1 |
| 36549465 | 2023 | Novel pathogenic variants in SLCO2A1 causing autosomal dominant primary hypertrophic osteoarthropathy. | 1 |
| 36706979 | 2023 | N-glycosylation modifies prostaglandin E(2) uptake by reducing cell surface expression of SLCO2A1. | 1 |
| 36731680 | 2023 | Elevated PGT promotes proliferation and inhibits cell apoptosis in preeclampsia by Erk signaling pathway. | 1 |
| 36907595 | 2023 | A Novel Chronic Enteropathy Associated with SLCO2A1 Gene Mutation: Enterography Findings in a Multicenter Korean Registry. | 1 |
| 37327083 | 2023 | Attenuated Expression of SLCO2A1 Caused by DNA Methylation in Pediatric Inflammatory Bowel Disease. | 0 |
Citation
Dessen P
SLCO2A1 (solute carrier organic anion transporter family member 2A1)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54642/slco2a1-(solute-carrier-organic-anion-transporter-family-member-2a1)
