Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8723
MIM: 605931
HGNC: 11175
Ensembl: ENSG00000114520
Variants:
dbSNP: 8723
ClinVar: 8723
TCGA: ENSG00000114520
COSMIC: SNX4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000114520 | ENST00000251775 | O95219 |
| ENSG00000114520 | ENST00000465505 | F8W9T3 |
| ENSG00000114520 | ENST00000471751 | F8WDD4 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Endocytosis | KEGG | ko04144 |
| Endocytosis | KEGG | hsa04144 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33468622 | 2021 | The phosphatidylinositol 3-phosphate-binding protein SNX4 controls ATG9A recycling and autophagy. | 17 |
| 33468622 | 2021 | The phosphatidylinositol 3-phosphate-binding protein SNX4 controls ATG9A recycling and autophagy. | 17 |
| 28109317 | 2017 | Sorting nexin-4 regulates β-amyloid production by modulating β-site-activating cleavage enzyme-1. | 20 |
| 28109317 | 2017 | Sorting nexin-4 regulates β-amyloid production by modulating β-site-activating cleavage enzyme-1. | 20 |
| 24690921 | 2014 | α-Taxilin interacts with sorting nexin 4 and participates in the recycling pathway of transferrin receptor. | 5 |
| 24690921 | 2014 | α-Taxilin interacts with sorting nexin 4 and participates in the recycling pathway of transferrin receptor. | 5 |
| 21973056 | 2012 | SNX-BAR-mediated endosome tubulation is co-ordinated with endosome maturation. | 79 |
| 21973056 | 2012 | SNX-BAR-mediated endosome tubulation is co-ordinated with endosome maturation. | 79 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 19529763 | 2009 | SNX4 in complex with clathrin and dynein: implications for endosome movement. | 19 |
| 19529763 | 2009 | SNX4 in complex with clathrin and dynein: implications for endosome movement. | 19 |
| 17319803 | 2007 | Phosphoinositide-regulated retrograde transport of ricin: crosstalk between hVps34 and sorting nexins. | 22 |
| 17994011 | 2007 | SNX4 coordinates endosomal sorting of TfnR with dynein-mediated transport into the endocytic recycling compartment. | 132 |
| 17319803 | 2007 | Phosphoinositide-regulated retrograde transport of ricin: crosstalk between hVps34 and sorting nexins. | 22 |
Citation
Dessen P
SNX4 (sorting nexin 4)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54653/cancer-prone-explorer/meetings/
