SNX9 (sorting nexin 9)

2014-08-01  

Identity

HGNC
LOCATION
6q25.3
LOCUSID
ALIAS
SDP1,SH3PX1,SH3PXD3A,WISP
FUSION GENES

Other Information

Locus ID:

NCBI: 51429
MIM: 605952
HGNC: 14973
Ensembl: ENSG00000130340

Variants:

dbSNP: 51429
ClinVar: 51429
TCGA: ENSG00000130340
COSMIC: SNX9

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000130340ENST00000392185Q9Y5X1
ENSG00000130340ENST00000614703A0A087WZW2
ENSG00000130340ENST00000614800A0A087WVE4

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
trans-Golgi Network Vesicle BuddingREACTOMER-HSA-199992
Clathrin derived vesicle buddingREACTOMER-HSA-421837
Golgi Associated Vesicle BiogenesisREACTOMER-HSA-432722
Clathrin-mediated endocytosisREACTOMER-HSA-8856828

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
367325072023Deletion of SNX9 alleviates CD8 T cell exhaustion for effective cellular cancer immunotherapy.12
367325072023Deletion of SNX9 alleviates CD8 T cell exhaustion for effective cellular cancer immunotherapy.12
350508502022SNX9-induced membrane tubulation regulates CD28 cluster stability and signalling.4
350508502022SNX9-induced membrane tubulation regulates CD28 cluster stability and signalling.4
307840762019SNX9 determines the surface levels of integrin β1 in vascular endothelial cells: Implication in poor prognosis of human colorectal cancers overexpressing SNX9.14
314304512019Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.21
307840762019SNX9 determines the surface levels of integrin β1 in vascular endothelial cells: Implication in poor prognosis of human colorectal cancers overexpressing SNX9.14
314304512019Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.21
296226752018Sorting nexin 9 (SNX9) regulates levels of the transmembrane ADAM9 at the cell surface.10
296226752018Sorting nexin 9 (SNX9) regulates levels of the transmembrane ADAM9 at the cell surface.10
282666222017Sorting Nexin 9 facilitates podocin endocytosis in the injured podocyte.5
286275152017Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission.39
282666222017Sorting Nexin 9 facilitates podocin endocytosis in the injured podocyte.5
286275152017Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission.39
266089092016Impaired SNX9 Expression in Immune Cells during Chronic Inflammation: Prognostic and Diagnostic Implications.14

Citation

Dessen P

SNX9 (sorting nexin 9)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54654/chromosome-explorer/submit-meetings/