Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6694
MIM: 602637
HGNC: 11256
Ensembl: ENSG00000072080
Variants:
dbSNP: 6694
ClinVar: 6694
TCGA: ENSG00000072080
COSMIC: SPP2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000072080 | ENST00000168148 | Q13103 |
| ENSG00000072080 | ENST00000373368 | Q13103 |
| ENSG00000072080 | ENST00000425558 | C9J6K0 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36883270 | 2023 | Secreted phosphoprotein 24 kD (Spp24) inhibits the growth of human osteosarcoma through the BMP-2/Smad signaling pathway. | 0 |
| 38448371 | 2023 | SPP2 plays a role in the tumorigenesis of hepatocellular carcinoma: A bioinformatic based analysis. | 0 |
| 36883270 | 2023 | Secreted phosphoprotein 24 kD (Spp24) inhibits the growth of human osteosarcoma through the BMP-2/Smad signaling pathway. | 0 |
| 38448371 | 2023 | SPP2 plays a role in the tumorigenesis of hepatocellular carcinoma: A bioinformatic based analysis. | 0 |
| 33481052 | 2021 | Secreted Phosphoprotein 24 is a Biomarker of Mineral Metabolism. | 2 |
| 33481052 | 2021 | Secreted Phosphoprotein 24 is a Biomarker of Mineral Metabolism. | 2 |
| 31849319 | 2019 | Association between the expression of secreted phosphoprotein - related genes and prognosis of human cancer. | 22 |
| 31849319 | 2019 | Association between the expression of secreted phosphoprotein - related genes and prognosis of human cancer. | 22 |
| 27793899 | 2016 | Secreted Phosphoprotein 24 kD Inhibits Growth of Human Prostate Cancer Cells Stimulated by BMP-2. | 9 |
| 27793899 | 2016 | Secreted Phosphoprotein 24 kD Inhibits Growth of Human Prostate Cancer Cells Stimulated by BMP-2. | 9 |
| 25339413 | 2015 | The bone matrix protein secreted phosphoprotein 24 kD (Spp24): bone metabolism regulator and starting material for biotherapeutic materials. | 5 |
| 25418420 | 2015 | A carboxy terminal BMP/TGF-β binding site in secreted phosphoprotein 24 kD independently affects BMP-2 activity. | 4 |
| 25501958 | 2015 | Spp24 derivatives stimulate a Gi-protein coupled receptor-Erk1/2 signaling pathway and modulate gene expressions in W-20-17 cells. | 2 |
| 26459573 | 2015 | SPP2 Mutations Cause Autosomal Dominant Retinitis Pigmentosa. | 15 |
| 25339413 | 2015 | The bone matrix protein secreted phosphoprotein 24 kD (Spp24): bone metabolism regulator and starting material for biotherapeutic materials. | 5 |
Citation
Dessen P
SPP2 (secreted phosphoprotein 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54665/spp2-(secreted-phosphoprotein-2)
