SSU72 (SSU72 homolog, RNA polymerase II CTD phosphatase)

2014-08-01  

Identity

HGNC
LOCATION
1p36.33
LOCUSID
ALIAS
HSPC182,PNAS-120
FUSION GENES

Other Information

Locus ID:

NCBI: 29101
MIM: 617680
HGNC: 25016
Ensembl: ENSG00000160075

Variants:

dbSNP: 29101
ClinVar: 29101
TCGA: ENSG00000160075
COSMIC: SSU72

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000160075ENST00000291386Q9NP77
ENSG00000160075ENST00000359060Q9NP77

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
mRNA surveillance pathwayKEGGko03015
mRNA surveillance pathwayKEGGhsa03015

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
332446422021Diverse and conserved roles of the protein Ssu72 in eukaryotes: from yeast to higher organisms.3
339175422021Ssu72 Dual-Specific Protein Phosphatase: From Gene to Diseases.4
332446422021Diverse and conserved roles of the protein Ssu72 in eukaryotes: from yeast to higher organisms.3
339175422021Ssu72 Dual-Specific Protein Phosphatase: From Gene to Diseases.4
309013322019Functional interaction of human Ssu72 with RNA polymerase II complexes.5
309013322019Functional interaction of human Ssu72 with RNA polymerase II complexes.5
291582572018Structural dissection of an interaction between transcription initiation and termination factors implicated in promoter-terminator cross-talk.9
291582572018Structural dissection of an interaction between transcription initiation and termination factors implicated in promoter-terminator cross-talk.9
241498582013Functional interplay between Aurora B kinase and Ssu72 phosphatase regulates sister chromatid cohesion.11
241498582013Functional interplay between Aurora B kinase and Ssu72 phosphatase regulates sister chromatid cohesion.11
230708122012An unexpected binding mode for a Pol II CTD peptide phosphorylated at Ser7 in the active site of the CTD phosphatase Ssu72.27
230708122012An unexpected binding mode for a Pol II CTD peptide phosphorylated at Ser7 in the active site of the CTD phosphatase Ssu72.27
208183332010The hsSsu72 phosphatase is a cohesin-binding protein that regulates the resolution of sister chromatid arm cohesion.10
208618392010Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex.102
208183332010The hsSsu72 phosphatase is a cohesin-binding protein that regulates the resolution of sister chromatid arm cohesion.10

Citation

Dessen P

SSU72 (SSU72 homolog, RNA polymerase II CTD phosphatase)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54671/ssu72-(ssu72-homolog-rna-polymerase-ii-ctd-phosphatase)