Identity
HGNC
LOCATION
19q13.12
LOCUSID
ALIAS
CG22,CKAP1,CKAPI
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1155
MIM: 601303
HGNC: 1989
Ensembl: ENSG00000105254
Variants:
dbSNP: 1155
ClinVar: 1155
TCGA: ENSG00000105254
COSMIC: TBCB
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Metabolism of proteins | REACTOME | R-HSA-392499 |
| Protein folding | REACTOME | R-HSA-391251 |
| Post-chaperonin tubulin folding pathway | REACTOME | R-HSA-389977 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 30030593 | 2018 | Dysregulation of a novel miR-1825/TBCB/TUBA4A pathway in sporadic and familial ALS. | 24 |
| 30030593 | 2018 | Dysregulation of a novel miR-1825/TBCB/TUBA4A pathway in sporadic and familial ALS. | 24 |
| 28393858 | 2017 | HILI destabilizes microtubules by suppressing phosphorylation and Gigaxonin-mediated degradation of TBCB. | 6 |
| 28393858 | 2017 | HILI destabilizes microtubules by suppressing phosphorylation and Gigaxonin-mediated degradation of TBCB. | 6 |
| 25505242 | 2015 | Microtubule-associated proteins 1 (MAP1) promote human immunodeficiency virus type I (HIV-1) intracytoplasmic routing to the nucleus. | 43 |
| 25908846 | 2015 | The structure of the complex between α-tubulin, TBCE and TBCB reveals a tubulin dimer dissociation mechanism. | 20 |
| 25505242 | 2015 | Microtubule-associated proteins 1 (MAP1) promote human immunodeficiency virus type I (HIV-1) intracytoplasmic routing to the nucleus. | 43 |
| 25908846 | 2015 | The structure of the complex between α-tubulin, TBCE and TBCB reveals a tubulin dimer dissociation mechanism. | 20 |
| 22940919 | 2013 | Autoinhibition of TBCB regulates EB1-mediated microtubule dynamics. | 8 |
| 22940919 | 2013 | Autoinhibition of TBCB regulates EB1-mediated microtubule dynamics. | 8 |
| 22777741 | 2012 | Tubulin-binding cofactor B is a direct interaction partner of the dynactin subunit p150(Glued). | 3 |
| 22777741 | 2012 | Tubulin-binding cofactor B is a direct interaction partner of the dynactin subunit p150(Glued). | 3 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 19038251 | 2009 | Tubulin cofactor B regulates microtubule densities during microglia transition to the reactive states. | 12 |
Citation
Dessen P
TBCB (tubulin folding cofactor B)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54692/tbcb-(tubulin-folding-cofactor-b)
