Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 64216
MIM: 607055
HGNC: 18559
Ensembl: ENSG00000162851
Variants:
dbSNP: 64216
ClinVar: 64216
TCGA: ENSG00000162851
COSMIC: TFB2M
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000162851 | ENST00000366514 | Q9H5Q4 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34744028 | 2022 | TFB2M and POLRMT are essential for mammalian mitochondrial DNA replication. | 6 |
| 35577351 | 2022 | Mitochondrial transcription factor B2 overexpression increases M2 macrophage infiltration via cytosolic mitochondrial DNA-stimulated Interleukin-6 secretion in ovarian cancer. | 1 |
| 34744028 | 2022 | TFB2M and POLRMT are essential for mammalian mitochondrial DNA replication. | 6 |
| 35577351 | 2022 | Mitochondrial transcription factor B2 overexpression increases M2 macrophage infiltration via cytosolic mitochondrial DNA-stimulated Interleukin-6 secretion in ovarian cancer. | 1 |
| 32174027 | 2020 | Over-expression of TFB2M facilitates cell growth and metastasis via activating ROS-Akt-NF-κB signalling in hepatocellular carcinoma. | 9 |
| 32505352 | 2020 | Phosphorylation of mitochondrial transcription factor B2 controls mitochondrial DNA binding and transcription. | 2 |
| 32174027 | 2020 | Over-expression of TFB2M facilitates cell growth and metastasis via activating ROS-Akt-NF-κB signalling in hepatocellular carcinoma. | 9 |
| 32505352 | 2020 | Phosphorylation of mitochondrial transcription factor B2 controls mitochondrial DNA binding and transcription. | 2 |
| 30414672 | 2018 | Identification of a rare homozygous c.790C>T variation in the TFB2M gene in Korean patients with autism spectrum disorder. | 4 |
| 30414672 | 2018 | Identification of a rare homozygous c.790C>T variation in the TFB2M gene in Korean patients with autism spectrum disorder. | 4 |
| 28028173 | 2017 | Human Mitochondrial Transcription Factor B2 Is Required for Promoter Melting during Initiation of Transcription. | 25 |
| 29149603 | 2017 | Structural Basis of Mitochondrial Transcription Initiation. | 86 |
| 28028173 | 2017 | Human Mitochondrial Transcription Factor B2 Is Required for Promoter Melting during Initiation of Transcription. | 25 |
| 29149603 | 2017 | Structural Basis of Mitochondrial Transcription Initiation. | 86 |
| 24413562 | 2014 | Organization of the human mitochondrial transcription initiation complex. | 23 |
Citation
Dessen P
TFB2M (transcription factor B2, mitochondrial)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54698/tfb2m-(transcription-factor-b2-mitochondrial)
