TMEM119 (transmembrane protein 119)

2014-08-01  

Identity

HGNC
LOCATION
12q23.3
LOCUSID
ALIAS
OBIF
FUSION GENES

Other Information

Locus ID:

NCBI: 338773
HGNC: 27884
Ensembl: ENSG00000183160

Variants:

dbSNP: 338773
ClinVar: 338773
TCGA: ENSG00000183160
COSMIC: TMEM119

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000183160ENST00000392806Q4V9L6
ENSG00000183160ENST00000547567F8VZL0
ENSG00000183160ENST00000549031F8VS22
ENSG00000183160ENST00000549447F8W0W9

Expression (GTEx)

0
50
100
150
200

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
384740682024TMEM119 (c.G143A, p.S48L) Mutation Is Involved in Primary Failure of Eruption by Attenuating Glycolysis-Mediated Osteogenesis.0
384740682024TMEM119 (c.G143A, p.S48L) Mutation Is Involved in Primary Failure of Eruption by Attenuating Glycolysis-Mediated Osteogenesis.0
337311242021TMEM119 facilitates ovarian cancer cell proliferation, invasion, and migration via the PDGFRB/PI3K/AKT signaling pathway.19
343341232021Transmembrane protein TMEM119 facilitates the stemness of breast cancer cells by activating Wnt/β-catenin pathway.14
337311242021TMEM119 facilitates ovarian cancer cell proliferation, invasion, and migration via the PDGFRB/PI3K/AKT signaling pathway.19
343341232021Transmembrane protein TMEM119 facilitates the stemness of breast cancer cells by activating Wnt/β-catenin pathway.14
327199592020TMEM119 as a specific marker of microglia reaction in traumatic brain injury in postmortem examination.21
327199592020TMEM119 as a specific marker of microglia reaction in traumatic brain injury in postmortem examination.21
318292832019Regulation of microglial TMEM119 and P2RY12 immunoreactivity in multiple sclerosis white and grey matter lesions is dependent on their inflammatory environment.68
318292832019Regulation of microglial TMEM119 and P2RY12 immunoreactivity in multiple sclerosis white and grey matter lesions is dependent on their inflammatory environment.68
284961992017Upregulation and biological function of transmembrane protein 119 in osteosarcoma.20
284961992017Upregulation and biological function of transmembrane protein 119 in osteosarcoma.20
262507882016TMEM119 marks a subset of microglia in the human brain.222
268841662016New tools for studying microglia in the mouse and human CNS.922
262507882016TMEM119 marks a subset of microglia in the human brain.222

Citation

Dessen P

TMEM119 (transmembrane protein 119)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54707/tmem119-(transmembrane-protein-119)