TPST2 (tyrosylprotein sulfotransferase 2)

2014-08-01  

Identity

HGNC
LOCATION
22q12.1
LOCUSID
ALIAS
TANGO13B,TPST-2
FUSION GENES

Other Information

Locus ID:

NCBI: 8459
MIM: 603126
HGNC: 12021
Ensembl: ENSG00000128294

Variants:

dbSNP: 8459
ClinVar: 8459
TCGA: ENSG00000128294
COSMIC: TPST2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000128294ENST00000338754O60704
ENSG00000128294ENST00000338754A0A024R1G9
ENSG00000128294ENST00000398110O60704
ENSG00000128294ENST00000398110A0A024R1G9
ENSG00000128294ENST00000403880O60704
ENSG00000128294ENST00000403880A0A024R1G9
ENSG00000128294ENST00000440953B1AHJ8
ENSG00000128294ENST00000442495B1AHJ6
ENSG00000128294ENST00000445720B1AHJ5
ENSG00000128294ENST00000450022B1AHK0
ENSG00000128294ENST00000453117B1AHJ9
ENSG00000128294ENST00000454778B1AHJ7

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
121696682002Tyrosine sulfation of CCR5 N-terminal peptide by tyrosylprotein sulfotransferases 1 and 2 follows a discrete pattern and temporal sequence.36
234813802013Crystal structure of human tyrosylprotein sulfotransferase-2 reveals the mechanism of protein tyrosine sulfation reaction.18
186723802008Mass spectrometric kinetic analysis of human tyrosylprotein sulfotransferase-1 and -2.14
193430462009Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.3
261089872015Computational Evidence for the Catalytic Mechanism of Tyrosylprotein Sulfotransferases: A Density Functional Theory Investigation.2
204609472010Sequence analysis of the human tyrosylprotein sulfotransferase-2 gene in subjects with chronic pancreatitis.1
204609472010Sequence analysis of the human tyrosylprotein sulfotransferase-2 gene in subjects with chronic pancreatitis.1
120568002002Shear stress mediates tyrosylprotein sulfotransferase isoform shift in human endothelial cells.0

Citation

Dessen P

TPST2 (tyrosylprotein sulfotransferase 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54719/tpst2-(tyrosylprotein-sulfotransferase-2)