TUBGCP3 (tubulin gamma complex associated protein 3)

2014-08-01  

Identity

HGNC
LOCATION
13q34
LOCUSID
ALIAS
104p,ALP6,GCP3,Grip104,SPBC98,Spc98,Spc98p
FUSION GENES

Other Information

Locus ID:

NCBI: 10426
MIM: 617818
HGNC: 18598
Ensembl: ENSG00000126216

Variants:

dbSNP: 10426
ClinVar: 10426
TCGA: ENSG00000126216
COSMIC: TUBGCP3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000126216ENST00000261965Q96CW5
ENSG00000126216ENST00000375669Q96CW5
ENSG00000126216ENST00000464139A0A087WU06
ENSG00000126216ENST00000611152A0A087WZV5
ENSG00000126216ENST00000649778A0A3B3ITE3

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
Cell CycleREACTOMER-HSA-1640170
Cell Cycle, MitoticREACTOMER-HSA-69278
Mitotic G2-G2/M phasesREACTOMER-HSA-453274
G2/M TransitionREACTOMER-HSA-69275
Centrosome maturationREACTOMER-HSA-380287
Recruitment of mitotic centrosome proteins and complexesREACTOMER-HSA-380270
Recruitment of NuMA to mitotic centrosomesREACTOMER-HSA-380320

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
345158752022CircTUBGCP3 Contributes to the Malignant Progression of Rectal Cancer.4
345158752022CircTUBGCP3 Contributes to the Malignant Progression of Rectal Cancer.4
288510272017NMR secondary structure and interactions of recombinant human MOZART1 protein, a component of the gamma-tubulin complex.5
288510272017NMR secondary structure and interactions of recombinant human MOZART1 protein, a component of the gamma-tubulin complex.5
260794482015Overexpression and Nucleolar Localization of γ-Tubulin Small Complex Proteins GCP2 and GCP3 in Glioblastoma.20
260794482015Overexpression and Nucleolar Localization of γ-Tubulin Small Complex Proteins GCP2 and GCP3 in Glioblastoma.20
238869392013Functional replacement of fission yeast γ-tubulin small complex proteins Alp4 and Alp6 by human GCP2 and GCP3.5
238869392013Functional replacement of fission yeast γ-tubulin small complex proteins Alp4 and Alp6 by human GCP2 and GCP3.5
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
208586832010Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways.231
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
208586832010Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways.231
192994672009Stability of the small gamma-tubulin complex requires HCA66, a protein of the centrosome and the nucleolus.13
192994672009Stability of the small gamma-tubulin complex requires HCA66, a protein of the centrosome and the nucleolus.13

Citation

Dessen P

TUBGCP3 (tubulin gamma complex associated protein 3)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54738/tubgcp3-(tubulin-gamma-complex-associated-protein-3)