Identity
HGNC
LOCATION
16p12.2
LOCUSID
ALIAS
MC3DN5,QCR2,UQCR2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7385
MIM: 191329
HGNC: 12586
Ensembl: ENSG00000140740
Variants:
dbSNP: 7385
ClinVar: 7385
TCGA: ENSG00000140740
COSMIC: UQCRC2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36509339 | 2023 | UQCRC2-related mitochondrial complex III deficiency, about 7 patients. | 2 |
| 36509339 | 2023 | UQCRC2-related mitochondrial complex III deficiency, about 7 patients. | 2 |
| 33719895 | 2021 | AMPK protects against alcohol-induced liver injury through UQCRC2 to up-regulate mitophagy. | 24 |
| 33865955 | 2021 | Homozygous missense mutation in UQCRC2 associated with severe encephalomyopathy, mitochondrial complex III assembly defect and activation of mitochondrial protein quality control. | 9 |
| 34565283 | 2021 | Circular RNA hsa_circ_0000751 serves as a microRNA-488 sponge to suppress gastric cancer progression via ubiquinol-cytochrome c reductase core protein 2 regulation. | 1 |
| 33719895 | 2021 | AMPK protects against alcohol-induced liver injury through UQCRC2 to up-regulate mitophagy. | 24 |
| 33865955 | 2021 | Homozygous missense mutation in UQCRC2 associated with severe encephalomyopathy, mitochondrial complex III assembly defect and activation of mitochondrial protein quality control. | 9 |
| 34565283 | 2021 | Circular RNA hsa_circ_0000751 serves as a microRNA-488 sponge to suppress gastric cancer progression via ubiquinol-cytochrome c reductase core protein 2 regulation. | 1 |
| 30674441 | 2019 | Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradation. | 8 |
| 30674441 | 2019 | Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradation. | 8 |
| 30078018 | 2018 | A Novel Tumor-Suppressor, CDH18, Inhibits Glioma Cell Invasiveness Via UQCRC2 and Correlates with the Prognosis of Glioma Patients. | 21 |
| 30115536 | 2018 | Overexpression of UQCRC2 is correlated with tumor progression and poor prognosis in colorectal cancer. | 14 |
| 30078018 | 2018 | A Novel Tumor-Suppressor, CDH18, Inhibits Glioma Cell Invasiveness Via UQCRC2 and Correlates with the Prognosis of Glioma Patients. | 21 |
| 30115536 | 2018 | Overexpression of UQCRC2 is correlated with tumor progression and poor prognosis in colorectal cancer. | 14 |
| 23281071 | 2013 | Mitochondrial complex III deficiency caused by a homozygous UQCRC2 mutation presenting with neonatal-onset recurrent metabolic decompensation. | 44 |
Citation
Dessen P
UQCRC2 (ubiquinol-cytochrome c reductase core protein 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54758/uqcrc2-(ubiquinol-cytochrome-c-reductase-core-protein-2)
