Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 64854
MIM: 612849
HGNC: 20075
Ensembl: ENSG00000109189
Variants:
dbSNP: 64854
ClinVar: 64854
TCGA: ENSG00000109189
COSMIC: USP46
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36335636 | 2023 | Ubiquitin specific protease 46 potentiates triple negative breast cancer development by stabilizing PGAM1-mediated glycolysis. | 1 |
| 37798301 | 2023 | The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling. | 4 |
| 36335636 | 2023 | Ubiquitin specific protease 46 potentiates triple negative breast cancer development by stabilizing PGAM1-mediated glycolysis. | 1 |
| 37798301 | 2023 | The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling. | 4 |
| 35637630 | 2022 | MiR-27a-3p targets USP46 to inhibit the cell proliferation of hepatocellular carcinoma. | 1 |
| 35637630 | 2022 | MiR-27a-3p targets USP46 to inhibit the cell proliferation of hepatocellular carcinoma. | 1 |
| 33576437 | 2021 | Downregulated expression levels of USP46 promote the resistance of ovarian cancer to cisplatin and are regulated by PUM2. | 4 |
| 34029571 | 2021 | Deubiquitinating enzyme USP46 suppresses the progression of hepatocellular carcinoma by stabilizing MST1. | 7 |
| 33576437 | 2021 | Downregulated expression levels of USP46 promote the resistance of ovarian cancer to cisplatin and are regulated by PUM2. | 4 |
| 34029571 | 2021 | Deubiquitinating enzyme USP46 suppresses the progression of hepatocellular carcinoma by stabilizing MST1. | 7 |
| 33029497 | 2020 | USP46 Inhibits Cell Proliferation in Lung Cancer through PHLPP1/AKT Pathway. | 4 |
| 33029497 | 2020 | USP46 Inhibits Cell Proliferation in Lung Cancer through PHLPP1/AKT Pathway. | 4 |
| 31542232 | 2019 | Ubiquitin-specific peptidase 46 (USP46) suppresses renal cell carcinoma tumorigenesis through AKT pathway inactivation. | 5 |
| 31542232 | 2019 | Ubiquitin-specific peptidase 46 (USP46) suppresses renal cell carcinoma tumorigenesis through AKT pathway inactivation. | 5 |
| 30415951 | 2018 | The Deubiquitinase USP46 Is Essential for Proliferation and Tumor Growth of HPV-Transformed Cancers. | 25 |
Citation
Dessen P
USP46 (ubiquitin specific peptidase 46)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54763/haematological-explorer/
