WDR70 (WD repeat domain 70)

2014-08-01  

Identity

HGNC
WDR70
LOCATION
5p13.2
LOCUSID
55100
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55100
MIM: 617233
HGNC: 25495
Ensembl: ENSG00000082068

Variants:

dbSNP: 55100
ClinVar: 55100
TCGA: ENSG00000082068
COSMIC: WDR70

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000082068ENST00000265107Q9NW82
ENSG00000082068ENST00000504564D6RIW8

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
376829912023Requirement of WDR70 for POLE3-mediated DNA double-strand breaks repair.1
376829912023Requirement of WDR70 for POLE3-mediated DNA double-strand breaks repair.1
291306592017[DNA Repair Function and Mutation of an H2B Monoubiquitination Factor WDR70 in Ovarian Cancer].0
291306592017[DNA Repair Function and Mutation of an H2B Monoubiquitination Factor WDR70 in Ovarian Cancer].0
270984972016CRL4(Wdr70) regulates H2B monoubiquitination and facilitates Exo1-dependent resection.27
270984972016CRL4(Wdr70) regulates H2B monoubiquitination and facilitates Exo1-dependent resection.27

Citation

Dessen P

WDR70 (WD repeat domain 70)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54779/wdr70-(wd-repeat-domain-70)