Identity
HGNC
LOCATION
7p22.1
LOCUSID
ALIAS
ATG18B,Atg21,CGI-50,IDDSSA,WIPI-2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 26100
MIM: 609225
HGNC: 32225
Ensembl: ENSG00000157954
Variants:
dbSNP: 26100
ClinVar: 26100
TCGA: ENSG00000157954
COSMIC: WIPI2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36872914 | 2023 | STING directly recruits WIPI2 for autophagosome formation during STING-induced autophagy. | 14 |
| 36872914 | 2023 | STING directly recruits WIPI2 for autophagosome formation during STING-induced autophagy. | 14 |
| 34505572 | 2021 | Structural basis for membrane recruitment of ATG16L1 by WIPI2 in autophagy. | 22 |
| 34505572 | 2021 | Structural basis for membrane recruitment of ATG16L1 by WIPI2 in autophagy. | 22 |
| 32323845 | 2020 | WIPI2 depletion inhibits the growth of hepatocellular carcinoma cells through the AMPK signaling pathway. | 8 |
| 32437499 | 2020 | A PI3K-WIPI2 positive feedback loop allosterically activates LC3 lipidation in autophagy. | 46 |
| 32323845 | 2020 | WIPI2 depletion inhibits the growth of hepatocellular carcinoma cells through the AMPK signaling pathway. | 8 |
| 32437499 | 2020 | A PI3K-WIPI2 positive feedback loop allosterically activates LC3 lipidation in autophagy. | 46 |
| 30968111 | 2019 | A mutation in the major autophagy gene, WIPI2, associated with global developmental abnormalities. | 21 |
| 30968111 | 2019 | A mutation in the major autophagy gene, WIPI2, associated with global developmental abnormalities. | 21 |
| 29133525 | 2018 | Optineurin promotes autophagosome formation by recruiting the autophagy-related Atg12-5-16L1 complex to phagophores containing the Wipi2 protein. | 33 |
| 30340022 | 2018 | mTORC1-Regulated and HUWE1-Mediated WIPI2 Degradation Controls Autophagy Flux. | 56 |
| 29133525 | 2018 | Optineurin promotes autophagosome formation by recruiting the autophagy-related Atg12-5-16L1 complex to phagophores containing the Wipi2 protein. | 33 |
| 30340022 | 2018 | mTORC1-Regulated and HUWE1-Mediated WIPI2 Degradation Controls Autophagy Flux. | 56 |
| 28760651 | 2017 | Evaluation of urinary autophagy transcripts expression in diabetic kidney disease. | 7 |
Citation
Dessen P
WIPI2 (WD repeat domain, phosphoinositide interacting 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54784/wipi2-(wd-repeat-domain-phosphoinositide-interacting-2)
