Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54464
MIM: 607994
HGNC: 30654
Ensembl: ENSG00000114127
Variants:
dbSNP: 54464
ClinVar: 54464
TCGA: ENSG00000114127
COSMIC: XRN1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36300942 | 2022 | Host 5'-3' Exoribonuclease XRN1 Acts as a Proviral Factor for Measles Virus Replication by Downregulating the dsRNA-Activated Kinase PKR. | 2 |
| 36300942 | 2022 | Host 5'-3' Exoribonuclease XRN1 Acts as a Proviral Factor for Measles Virus Replication by Downregulating the dsRNA-Activated Kinase PKR. | 2 |
| 34266995 | 2021 | Genome-wide analyses of XRN1-sensitive targets in osteosarcoma cells identify disease-relevant transcripts containing G-rich motifs. | 0 |
| 34311580 | 2021 | Cellular 5'-3' mRNA Exoribonuclease XRN1 Inhibits Interferon Beta Activation and Facilitates Influenza A Virus Replication. | 10 |
| 34611223 | 2021 | Dysregulated non-coding telomerase RNA component and associated exonuclease XRN1 in leucocytes from women developing preeclampsia-possible link to enhanced senescence. | 3 |
| 34266995 | 2021 | Genome-wide analyses of XRN1-sensitive targets in osteosarcoma cells identify disease-relevant transcripts containing G-rich motifs. | 0 |
| 34311580 | 2021 | Cellular 5'-3' mRNA Exoribonuclease XRN1 Inhibits Interferon Beta Activation and Facilitates Influenza A Virus Replication. | 10 |
| 34611223 | 2021 | Dysregulated non-coding telomerase RNA component and associated exonuclease XRN1 in leucocytes from women developing preeclampsia-possible link to enhanced senescence. | 3 |
| 31116665 | 2019 | mRNA levels are buffered upon knockdown of RNA decay and translation factors via adjustment of transcription rates in human HepG2 cells. | 12 |
| 31340047 | 2019 | A low-complexity region in human XRN1 directly recruits deadenylation and decapping factors in 5'-3' messenger RNA decay. | 19 |
| 31116665 | 2019 | mRNA levels are buffered upon knockdown of RNA decay and translation factors via adjustment of transcription rates in human HepG2 cells. | 12 |
| 31340047 | 2019 | A low-complexity region in human XRN1 directly recruits deadenylation and decapping factors in 5'-3' messenger RNA decay. | 19 |
| 29100804 | 2018 | Immunohistochemical localization of exoribonucleases (DIS3L2 and XRN1) in intranuclear inclusion body disease. | 7 |
| 29118186 | 2018 | Identification of phlebovirus and arenavirus RNA sequences that stall and repress the exoribonuclease XRN1. | 20 |
| 29465287 | 2018 | The exoribonuclease Xrn1 is a post-transcriptional negative regulator of autophagy. | 25 |
Citation
Dessen P
XRN1 (5-3 exoribonuclease 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54788/
