Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1670
MIM: 600472
HGNC: 2764
Ensembl: ENSG00000164816
Variants:
dbSNP: 1670
ClinVar: 1670
TCGA: ENSG00000164816
COSMIC: DEFA5
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000164816 | ENST00000330590 | Q01523 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38330831 | 2024 | Human Intestinal Defensin 5 Ameliorates the Sensitization of Colonic Cancer Cells to 5-Fluorouracil. | 0 |
| 38330831 | 2024 | Human Intestinal Defensin 5 Ameliorates the Sensitization of Colonic Cancer Cells to 5-Fluorouracil. | 0 |
| 37277970 | 2023 | Association between α-defensin 5 and the expression and function of P-glycoprotein in differentiated intestinal Caco-2 cells. | 0 |
| 37598668 | 2023 | Reduced DEFA5 Expression and STAT3 Activation Underlie the Submucosal Invasion of Early Gastric Cancers. | 0 |
| 37861034 | 2023 | The Function and Modification of Human Defensin 5. | 0 |
| 37277970 | 2023 | Association between α-defensin 5 and the expression and function of P-glycoprotein in differentiated intestinal Caco-2 cells. | 0 |
| 37598668 | 2023 | Reduced DEFA5 Expression and STAT3 Activation Underlie the Submucosal Invasion of Early Gastric Cancers. | 0 |
| 37861034 | 2023 | The Function and Modification of Human Defensin 5. | 0 |
| 34105106 | 2022 | Lower human defensin 5 in elderly people compared to middle-aged is associated with differences in the intestinal microbiota composition: the DOSANCO Health Study. | 11 |
| 36632813 | 2022 | 3' untranslated region variants in DEFA5 gene associated with susceptibility to IgA nephropathy in the Chinese Han population. | 0 |
| 34105106 | 2022 | Lower human defensin 5 in elderly people compared to middle-aged is associated with differences in the intestinal microbiota composition: the DOSANCO Health Study. | 11 |
| 36632813 | 2022 | 3' untranslated region variants in DEFA5 gene associated with susceptibility to IgA nephropathy in the Chinese Han population. | 0 |
| 33503272 | 2021 | The inhibitory effect of human DEFA5 in growth of gastric cancer by targeting BMI1. | 11 |
| 33690604 | 2021 | Linking bacterial enterotoxins and alpha defensin 5 expansion in the Crohn's colitis: A new insight into the etiopathogenetic and differentiation triggers driving colonic inflammatory bowel disease. | 11 |
| 34487729 | 2021 | Human α-defensin 5 suppressed colon cancer growth by targeting PI3K pathway. | 6 |
Citation
Dessen P
DEFA5 (defensin alpha 5)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54832/defa5-(defensin-alpha-5)
