ZKSCAN1 (zinc finger with KRAB and SCAN domains 1)

2014-08-01  

Identity

HGNC
LOCATION
7q22.1
LOCUSID
ALIAS
KOX18,PHZ-37,ZNF139,ZNF36,ZSCAN33
FUSION GENES

Other Information

Locus ID:

NCBI: 7586
MIM: 601260
HGNC: 13101
Ensembl: ENSG00000106261

Variants:

dbSNP: 7586
ClinVar: 7586
TCGA: ENSG00000106261
COSMIC: ZKSCAN1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000106261ENST00000324306P17029
ENSG00000106261ENST00000426572E9PC66
ENSG00000106261ENST00000432317C9JRM9
ENSG00000106261ENST00000535170B3KRF7
ENSG00000106261ENST00000620510E9PC66

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
366910312023A novel polypeptide encoded by the circular RNA ZKSCAN1 suppresses HCC via degradation of mTOR.16
366910312023A novel polypeptide encoded by the circular RNA ZKSCAN1 suppresses HCC via degradation of mTOR.16
334393972021CircZKSCAN1 Suppresses Hepatocellular Carcinoma Tumorigenesis by Regulating miR-873-5p/Downregulation of Deleted in Liver Cancer 1.6
334393972021CircZKSCAN1 Suppresses Hepatocellular Carcinoma Tumorigenesis by Regulating miR-873-5p/Downregulation of Deleted in Liver Cancer 1.6
312814952019Circular RNAs negatively regulate cancer stem cells by physically binding FMRP against CCAR1 complex in hepatocellular carcinoma.130
314810662019Circular RNA circ-ZKSCAN1 inhibits bladder cancer progression through miR-1178-3p/p21 axis and acts as a prognostic factor of recurrence.67
312814952019Circular RNAs negatively regulate cancer stem cells by physically binding FMRP against CCAR1 complex in hepatocellular carcinoma.130
314810662019Circular RNA circ-ZKSCAN1 inhibits bladder cancer progression through miR-1178-3p/p21 axis and acts as a prognostic factor of recurrence.67
299568112018miR‑195‑5p regulates multi‑drug resistance of gastric cancer cells via targeting ZNF139.17
301268482018ZNF139 increases multidrug resistance in gastric cancer cells by inhibiting miR-185.17
299568112018miR‑195‑5p regulates multi‑drug resistance of gastric cancer cells via targeting ZNF139.17
301268482018ZNF139 increases multidrug resistance in gastric cancer cells by inhibiting miR-185.17
282112152017ZKSCAN1 gene and its related circular RNA (circZKSCAN1) both inhibit hepatocellular carcinoma cell growth, migration, and invasion but through different signaling pathways.175
282112152017ZKSCAN1 gene and its related circular RNA (circZKSCAN1) both inhibit hepatocellular carcinoma cell growth, migration, and invasion but through different signaling pathways.175
267224292015Silencing of ZNF139-siRNA induces apoptosis in human gastric cancer cell line BGC823.9

Citation

Dessen P

ZKSCAN1 (zinc finger with KRAB and SCAN domains 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54840/zkscan1-(zinc-finger-with-krab-and-scan-domains-1)