Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5729
MIM: 604687
HGNC: 9591
Ensembl: ENSG00000168229
Variants:
dbSNP: 5729
ClinVar: 5729
TCGA: ENSG00000168229
COSMIC: PTGDR
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000168229 | ENST00000306051 | Q13258 |
| ENSG00000168229 | ENST00000553372 | Q13258 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA166129564 | laropiprant | Chemical | MultilinkAnnotation | associated | 26226939 | ||
| PA175 | GNAS | Gene | Pathway | associated | 20938371 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36916084 | 2023 | ATP2B1-AS1 exacerbates sepsis-induced cell apoptosis and inflammation by regulating miR-23a-3p/TLR4 axis. | 1 |
| 37805663 | 2023 | The ASH1L-AS1-ASH1L axis controls NME1-mediated activation of the RAS signaling in gastric cancer. | 2 |
| 36916084 | 2023 | ATP2B1-AS1 exacerbates sepsis-induced cell apoptosis and inflammation by regulating miR-23a-3p/TLR4 axis. | 1 |
| 37805663 | 2023 | The ASH1L-AS1-ASH1L axis controls NME1-mediated activation of the RAS signaling in gastric cancer. | 2 |
| 34750492 | 2022 | High PGD(2) receptor 2 levels are associated with poor prognosis in colorectal cancer patients and induce VEGF expression in colon cancer cells and migration in a zebrafish xenograft model. | 6 |
| 34750492 | 2022 | High PGD(2) receptor 2 levels are associated with poor prognosis in colorectal cancer patients and induce VEGF expression in colon cancer cells and migration in a zebrafish xenograft model. | 6 |
| 31062691 | 2020 | Promoter Genotyping and mRNA Expression - Based Analysis of the PTGDR Gene in Allergy. | 2 |
| 31917615 | 2020 | Loss of DP1 Aggravates Vascular Remodeling in Pulmonary Arterial Hypertension via mTORC1 Signaling. | 32 |
| 32334026 | 2020 | GGA3 interacts with L-type prostaglandin D synthase and regulates the recycling and signaling of the DP1 receptor for prostaglandin D(2) in a Rab4-dependent mechanism. | 0 |
| 31062691 | 2020 | Promoter Genotyping and mRNA Expression - Based Analysis of the PTGDR Gene in Allergy. | 2 |
| 31917615 | 2020 | Loss of DP1 Aggravates Vascular Remodeling in Pulmonary Arterial Hypertension via mTORC1 Signaling. | 32 |
| 32334026 | 2020 | GGA3 interacts with L-type prostaglandin D synthase and regulates the recycling and signaling of the DP1 receptor for prostaglandin D(2) in a Rab4-dependent mechanism. | 0 |
| 31575663 | 2019 | L-type prostaglandin D synthase regulates the trafficking of the PGD(2) DP1 receptor by interacting with the GTPase Rab4. | 3 |
| 31575663 | 2019 | L-type prostaglandin D synthase regulates the trafficking of the PGD(2) DP1 receptor by interacting with the GTPase Rab4. | 3 |
| 29607536 | 2018 | DP1 receptor signaling prevents the onset of intrinsic apoptosis in eosinophils and functions as a transcriptional modulator. | 7 |
Citation
Dessen P
PTGDR (prostaglandin D2 receptor)
Atlas Genet Cytogenet Oncol Haematol. 2014-09-01
Online version: http://atlasgeneticsoncology.org/gene/54851/ptgdr-(prostaglandin-d2-receptor)
