Identity
HGNC
LOCATION
6p25.2
LOCUSID
ALIAS
EI,ELANH2,HEL-S-27,HEL57,LEI,M/NEI,MNEI,PI-2,PI2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1992
MIM: 130135
HGNC: 3311
Ensembl: ENSG00000021355
Variants:
dbSNP: 1992
ClinVar: 1992
TCGA: ENSG00000021355
COSMIC: SERPINB1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000021355 | ENST00000380739 | P30740 |
| ENSG00000021355 | ENST00000380739 | V9HWH1 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Amoebiasis | KEGG | ko05146 |
| Amoebiasis | KEGG | hsa05146 |
| Immune System | REACTOME | R-HSA-168256 |
| Innate Immune System | REACTOME | R-HSA-168249 |
| Neutrophil degranulation | REACTOME | R-HSA-6798695 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36730076 | 2023 | A proteomic analysis of NETosis in trauma: Emergence of serpinB1 as a key player. | 3 |
| 36730076 | 2023 | A proteomic analysis of NETosis in trauma: Emergence of serpinB1 as a key player. | 3 |
| 35291946 | 2022 | SERPINB1 overexpression protects myocardial damage induced by acute myocardial infarction through AMPK/mTOR pathway. | 2 |
| 35291946 | 2022 | SERPINB1 overexpression protects myocardial damage induced by acute myocardial infarction through AMPK/mTOR pathway. | 2 |
| 32903749 | 2020 | A Novel SERPINB1 Single-Nucleotide Polymorphism Associated With Glycemic Control and β-Cell Function in Egyptian Type 2 Diabetic Patients. | 5 |
| 32903749 | 2020 | A Novel SERPINB1 Single-Nucleotide Polymorphism Associated With Glycemic Control and β-Cell Function in Egyptian Type 2 Diabetic Patients. | 5 |
| 30610107 | 2019 | Epigenetic Suppression of SERPINB1 Promotes Inflammation-Mediated Prostate Cancer Progression. | 14 |
| 30692621 | 2019 | SERPINB1-mediated checkpoint of inflammatory caspase activation. | 59 |
| 30843084 | 2019 | Serpin B1 defect and increased apoptosis of neutrophils in Cohen syndrome neutropenia. | 11 |
| 30610107 | 2019 | Epigenetic Suppression of SERPINB1 Promotes Inflammation-Mediated Prostate Cancer Progression. | 14 |
| 30692621 | 2019 | SERPINB1-mediated checkpoint of inflammatory caspase activation. | 59 |
| 30843084 | 2019 | Serpin B1 defect and increased apoptosis of neutrophils in Cohen syndrome neutropenia. | 11 |
| 29967939 | 2018 | Sex-specific genetic predictors of Alzheimer's disease biomarkers. | 59 |
| 29967939 | 2018 | Sex-specific genetic predictors of Alzheimer's disease biomarkers. | 59 |
| 28005267 | 2017 | Human gingiva transcriptome during wound healing. | 14 |
Citation
Dessen P
SERPINB1 (serpin family B member 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-09-01
Online version: http://atlasgeneticsoncology.org/gene/54855/serpinb1-(serpin-family-b-member-1)
