DSCC1 (DNA replication and sister chromatid cohesion 1)

2014-09-01  

Identity

HGNC
LOCATION
8q24.12
LOCUSID
ALIAS
DCC1
FUSION GENES

Other Information

Locus ID:

NCBI: 79075
MIM: 613203
HGNC: 24453
Ensembl: ENSG00000136982

Variants:

dbSNP: 79075
ClinVar: 79075
TCGA: ENSG00000136982
COSMIC: DSCC1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000136982ENST00000313655Q9BVC3

Expression (GTEx)

0
5
10
15
20

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
386786042024Characterization of the prognostic, diagnostic, and immunological roles of DSCC1 and its genomic alteration and instability in human cancers.0
386786042024Characterization of the prognostic, diagnostic, and immunological roles of DSCC1 and its genomic alteration and instability in human cancers.0
331842432020DNA replication and sister chromatid cohesion 1 promotes breast carcinoma progression by modulating the Wnt/β-catenin signaling and p53 protein.6
331842432020DNA replication and sister chromatid cohesion 1 promotes breast carcinoma progression by modulating the Wnt/β-catenin signaling and p53 protein.6
244656812014Overexpression of cohesion establishment factor DSCC1 through E2F in colorectal cancer.16
244656812014Overexpression of cohesion establishment factor DSCC1 through E2F in colorectal cancer.16
208267852010Stable interaction between the human proliferating cell nuclear antigen loader complex Ctf18-replication factor C (RFC) and DNA polymerase {epsilon} is mediated by the cohesion-specific subunits, Ctf18, Dcc1, and Ctf8.31
208267852010Stable interaction between the human proliferating cell nuclear antigen loader complex Ctf18-replication factor C (RFC) and DNA polymerase {epsilon} is mediated by the cohesion-specific subunits, Ctf18, Dcc1, and Ctf8.31
127661762003Cloning and characterization of hCTF18, hCTF8, and hDCC1. Human homologs of a Saccharomyces cerevisiae complex involved in sister chromatid cohesion establishment.28
129309022003The alternative Ctf18-Dcc1-Ctf8-replication factor C complex required for sister chromatid cohesion loads proliferating cell nuclear antigen onto DNA.68
127661762003Cloning and characterization of hCTF18, hCTF8, and hDCC1. Human homologs of a Saccharomyces cerevisiae complex involved in sister chromatid cohesion establishment.28
129309022003The alternative Ctf18-Dcc1-Ctf8-replication factor C complex required for sister chromatid cohesion loads proliferating cell nuclear antigen onto DNA.68

Citation

Dessen P

DSCC1 (DNA replication and sister chromatid cohesion 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-09-01

Online version: http://atlasgeneticsoncology.org/gene/54861/dscc1-(dna-replication-and-sister-chromatid-cohesion-1)