Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 155061
MIM: 613914
HGNC: 21948
Ensembl: ENSG00000181220
Variants:
dbSNP: 155061
ClinVar: 155061
TCGA: ENSG00000181220
COSMIC: ZNF746
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000181220 | ENST00000340622 | Q6NUN9 |
| ENSG00000181220 | ENST00000458143 | Q6NUN9 |
| ENSG00000181220 | ENST00000461958 | C9JNZ9 |
| ENSG00000181220 | ENST00000644635 | A0A2R8YDQ5 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Gene Expression | REACTOME | R-HSA-74160 |
| Generic Transcription Pathway | REACTOME | R-HSA-212436 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38103579 | 2024 | Unveiling the regulatory of miR-101-3p on ZNF746 in a Parkinson's disease cell model: Implications for therapeutic targeting. | 1 |
| 38103579 | 2024 | Unveiling the regulatory of miR-101-3p on ZNF746 in a Parkinson's disease cell model: Implications for therapeutic targeting. | 1 |
| 37730102 | 2023 | ZNF746 promotes M2 macrophage polarisation and favours tumour progression in breast cancer via the Jagged1/Notch pathway. | 0 |
| 37870275 | 2023 | PARIS undergoes liquid-liquid phase separation and poly(ADP-ribose)-mediated solidification. | 1 |
| 37730102 | 2023 | ZNF746 promotes M2 macrophage polarisation and favours tumour progression in breast cancer via the Jagged1/Notch pathway. | 0 |
| 37870275 | 2023 | PARIS undergoes liquid-liquid phase separation and poly(ADP-ribose)-mediated solidification. | 1 |
| 33723766 | 2021 | Genetic Analysis of ZNF Protein Family Members for Early-Onset Parkinson's Disease in Chinese Population. | 8 |
| 34062393 | 2021 | ZNF746/PARIS promotes the occurrence of hepatocellular carcinoma. | 7 |
| 33723766 | 2021 | Genetic Analysis of ZNF Protein Family Members for Early-Onset Parkinson's Disease in Chinese Population. | 8 |
| 34062393 | 2021 | ZNF746/PARIS promotes the occurrence of hepatocellular carcinoma. | 7 |
| 32138754 | 2020 | PARIS induced defects in mitochondrial biogenesis drive dopamine neuron loss under conditions of parkin or PINK1 deficiency. | 45 |
| 32197837 | 2020 | RNF4-mediated SUMO-targeted ubiquitination relieves PARIS/ZNF746-mediated transcriptional repression. | 5 |
| 33077496 | 2020 | PARIS-DJ-1 Interaction Regulates Mitochondrial Functions in Cardiomyocytes, Which Is Critically Important in Cardiac Hypertrophy. | 4 |
| 32138754 | 2020 | PARIS induced defects in mitochondrial biogenesis drive dopamine neuron loss under conditions of parkin or PINK1 deficiency. | 45 |
| 32197837 | 2020 | RNF4-mediated SUMO-targeted ubiquitination relieves PARIS/ZNF746-mediated transcriptional repression. | 5 |
Citation
Dessen P
ZNF746 (zinc finger protein 746)
Atlas Genet Cytogenet Oncol Haematol. 2014-09-01
Online version: http://atlasgeneticsoncology.org/gene/54866/
