LDLRAD4 (low density lipoprotein receptor class A domain containing 4)

2014-09-01  

Identity

HGNC
LDLRAD4
LOCATION
18p11.21
LOCUSID
753
ALIAS
C18orf1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 753
MIM: 606571
HGNC: 1224
Ensembl: ENSG00000168675

Variants:

dbSNP: 753
ClinVar: 753
TCGA: ENSG00000168675
COSMIC: LDLRAD4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000168675ENST00000359446O15165
ENSG00000168675ENST00000399848O15165
ENSG00000168675ENST00000585931O15165
ENSG00000168675ENST00000586222K7EKD6
ENSG00000168675ENST00000586765O15165
ENSG00000168675ENST00000587757O15165
ENSG00000168675ENST00000587905K7EJM9
ENSG00000168675ENST00000592991O15165
ENSG00000168675ENST00000593236K7EMG1

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
325073642020Identification of low-density lipoprotein receptor class A domain containing 4 (LDLRAD4) as a prognostic indicator in primary gastrointestinal stromal tumors.4
325073642020Identification of low-density lipoprotein receptor class A domain containing 4 (LDLRAD4) as a prognostic indicator in primary gastrointestinal stromal tumors.4
288889372017Low density lipoprotein receptor class A domain containing 4 (LDLRAD4) promotes tumorigenesis of hepatic cancer cells.9
288889372017Low density lipoprotein receptor class A domain containing 4 (LDLRAD4) promotes tumorigenesis of hepatic cancer cells.9
246274872014C18 ORF1, a novel negative regulator of transforming growth factor-β signaling.33
246274872014C18 ORF1, a novel negative regulator of transforming growth factor-β signaling.33
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
194304792009Genome-wide association study of blood pressure and hypertension.662
198345352009Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging.29
194304792009Genome-wide association study of blood pressure and hypertension.662
198345352009Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging.29

Citation

Dessen P

LDLRAD4 (low density lipoprotein receptor class A domain containing 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-09-01

Online version: http://atlasgeneticsoncology.org/gene/54867/teaching-explorer/meetings/hgnc