STK26 (serine/threonine kinase 26)

2014-09-01  

Identity

HGNC
LOCATION
Xq26.2
LOCUSID
ALIAS
MASK,MST4

Other Information

Locus ID:

NCBI: 51765
MIM: 300547
HGNC: 18174
Ensembl: ENSG00000134602

Variants:

dbSNP: 51765
ClinVar: 51765
TCGA: ENSG00000134602
COSMIC: STK26

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000134602ENST00000354719Q8NBY1
ENSG00000134602ENST00000394334Q9P289
ENSG00000134602ENST00000394335Q9P289
ENSG00000134602ENST00000481105B4E0Y9
ENSG00000134602ENST00000496850Q9P289

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

Pathways

PathwaySourceExternal ID
Programmed Cell DeathREACTOMER-HSA-5357801
ApoptosisREACTOMER-HSA-109581
Apoptotic execution phaseREACTOMER-HSA-75153
Apoptotic cleavage of cellular proteinsREACTOMER-HSA-111465

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
385799912024Mst4, a novel cardiac STRIPAK complex-associated kinase, regulates cardiomyocyte growth and survival and is upregulated in human cardiomyopathy.0
385799912024Mst4, a novel cardiac STRIPAK complex-associated kinase, regulates cardiomyocyte growth and survival and is upregulated in human cardiomyopathy.0
370947362023The mammalian Sterile 20-like kinase 4 (MST4) signaling in tumor progression: Implications for therapy.1
374900002023STE20-type kinases MST3 and MST4 promote the progression of hepatocellular carcinoma: Evidence from human cell culture and expression profiling of liver biopsies.1
378334012023MST4 kinase regulates immune thrombocytopenia by phosphorylating STAT1-mediated M1 polarization of macrophages.1
370947362023The mammalian Sterile 20-like kinase 4 (MST4) signaling in tumor progression: Implications for therapy.1
374900002023STE20-type kinases MST3 and MST4 promote the progression of hepatocellular carcinoma: Evidence from human cell culture and expression profiling of liver biopsies.1
378334012023MST4 kinase regulates immune thrombocytopenia by phosphorylating STAT1-mediated M1 polarization of macrophages.1
365528282022MST4: A Potential Oncogene and Therapeutic Target in Breast Cancer.4
365528282022MST4: A Potential Oncogene and Therapeutic Target in Breast Cancer.4
342405842021An MST4-pβ-Catenin(Thr40) Signaling Axis Controls Intestinal Stem Cell and Tumorigenesis.11
342405842021An MST4-pβ-Catenin(Thr40) Signaling Axis Controls Intestinal Stem Cell and Tumorigenesis.11
314643462020A network-based variable selection approach for identification of modules and biomarker genes associated with end-stage kidney disease.4
322718802020MST4 kinase suppresses gastric tumorigenesis by limiting YAP activation via a non-canonical pathway.33
323405252020Tripartite motif containing 59 (TRIM59) promotes esophageal cancer progression via promoting MST4 expression and ERK pathway.1

Citation

Dessen P

STK26 (serine/threonine kinase 26)

Atlas Genet Cytogenet Oncol Haematol. 2014-09-01

Online version: http://atlasgeneticsoncology.org/gene/54887/stk26-(serine-threonine-kinase-26)