Identity
HGNC
LOCATION
Xq27.1
LOCUSID
ALIAS
GHDX,MRGH,PHP,PHPX,SOXB
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6658
MIM: 313430
HGNC: 11199
Ensembl: ENSG00000134595
Variants:
dbSNP: 6658
ClinVar: 6658
TCGA: ENSG00000134595
COSMIC: SOX3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000134595 | ENST00000370536 | P41225 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38927713 | 2024 | Clinical Correlation of Transcription Factor SOX3 in Cancer: Unveiling Its Role in Tumorigenesis. | 0 |
| 38927713 | 2024 | Clinical Correlation of Transcription Factor SOX3 in Cancer: Unveiling Its Role in Tumorigenesis. | 0 |
| 37216008 | 2023 | A complex structural variant near SOX3 causes X-linked split-hand/foot malformation. | 0 |
| 37749917 | 2023 | ROR2 deficit may induce the tetralogy of Fallot via down-regulating of β-catenin/SOX3/HSPA6 in vitro and in vivo. | 1 |
| 37216008 | 2023 | A complex structural variant near SOX3 causes X-linked split-hand/foot malformation. | 0 |
| 37749917 | 2023 | ROR2 deficit may induce the tetralogy of Fallot via down-regulating of β-catenin/SOX3/HSPA6 in vitro and in vivo. | 1 |
| 35098650 | 2022 | A SOX3 duplication and lumbosacral spina bifida in three generations. | 1 |
| 35275355 | 2022 | LINC00662 Promotes Proliferation and Invasion and Inhibits Apoptosis of Glioma Cells Through miR-483-3p/SOX3 Axis. | 3 |
| 36175695 | 2022 | Transcription factor SOX3 upregulated pro-apoptotic genes expression in human breast cancer. | 2 |
| 35098650 | 2022 | A SOX3 duplication and lumbosacral spina bifida in three generations. | 1 |
| 35275355 | 2022 | LINC00662 Promotes Proliferation and Invasion and Inhibits Apoptosis of Glioma Cells Through miR-483-3p/SOX3 Axis. | 3 |
| 36175695 | 2022 | Transcription factor SOX3 upregulated pro-apoptotic genes expression in human breast cancer. | 2 |
| 34440302 | 2021 | Allelic Variants in Established Hypopituitarism Genes Expand Our Knowledge of the Phenotypic Spectrum. | 0 |
| 34440302 | 2021 | Allelic Variants in Established Hypopituitarism Genes Expand Our Knowledge of the Phenotypic Spectrum. | 0 |
| 26352083 | 2020 | Marked phenotypic variable expression among brothers with duplication of Xq27.1 involving the SOX3 gene. | 2 |
Citation
Dessen P
SOX3 (SRY-box transcription factor 3)
Atlas Genet Cytogenet Oncol Haematol. 2014-09-01
Online version: http://atlasgeneticsoncology.org/gene/54895/sox3-(sry-box-transcription-factor-3)
