VSIG4 (V-set and immunoglobulin domain containing 4)

2014-09-01  

Identity

HGNC
LOCATION
Xq12
LOCUSID
ALIAS
CRIg,Z39IG
FUSION GENES

Other Information

Locus ID:

NCBI: 11326
MIM: 300353
HGNC: 17032
Ensembl: ENSG00000155659

Variants:

dbSNP: 11326
ClinVar: 11326
TCGA: ENSG00000155659
COSMIC: VSIG4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000155659ENST00000374737Q9Y279
ENSG00000155659ENST00000412866Q9Y279
ENSG00000155659ENST00000427538H7C062
ENSG00000155659ENST00000455586Q9Y279
ENSG00000155659ENST00000651578A0A494C0F5

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Complement and coagulation cascadesKEGGko04610
Complement and coagulation cascadesKEGGhsa04610

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
381136492024VSIG4 ameliorates intestinal inflammation through inhibiting macrophages NLRP3 inflammasome and pyroptosis.1
381136492024VSIG4 ameliorates intestinal inflammation through inhibiting macrophages NLRP3 inflammasome and pyroptosis.1
371634492023V-Set Immunoglobulin Domain-Containing Protein 4 as a Novel Serum Biomarker of Lupus Nephritis and Renal Pathology Activity.2
371634492023V-Set Immunoglobulin Domain-Containing Protein 4 as a Novel Serum Biomarker of Lupus Nephritis and Renal Pathology Activity.2
336450072021Impact of VSIG4 gene polymorphisms on susceptibility and functional status of rheumatoid arthritis.4
339043782021Rab18 interacted with V-set and immunoglobulin domain-containing 4 (VSIG4) to involve in the apoptosis of glioma and the sensitivity to temozolomide.4
348874052021CRIg on liver macrophages clears pathobionts and protects against alcoholic liver disease.18
336450072021Impact of VSIG4 gene polymorphisms on susceptibility and functional status of rheumatoid arthritis.4
339043782021Rab18 interacted with V-set and immunoglobulin domain-containing 4 (VSIG4) to involve in the apoptosis of glioma and the sensitivity to temozolomide.4
348874052021CRIg on liver macrophages clears pathobionts and protects against alcoholic liver disease.18
312666322019Expression of Vsig4 attenuates macrophage-mediated hepatic inflammation and fibrosis in high fat diet (HFD)-induced mice.7
312666322019Expression of Vsig4 attenuates macrophage-mediated hepatic inflammation and fibrosis in high fat diet (HFD)-induced mice.7
292680302018Inhibition of Macrophage Complement Receptor CRIg by TRIM72 Polarizes Innate Immunity of the Lung.11
304292872018Complement Inhibitor CRIg/FH Ameliorates Renal Ischemia Reperfusion Injury via Activation of PI3K/AKT Signaling.17
292680302018Inhibition of Macrophage Complement Receptor CRIg by TRIM72 Polarizes Innate Immunity of the Lung.11

Citation

Dessen P

VSIG4 (V-set and immunoglobulin domain containing 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-09-01

Online version: http://atlasgeneticsoncology.org/gene/54897/vsig4-(v-set-and-immunoglobulin-domain-containing-4)