CREB5 (cAMP responsive element binding protein 5)

2014-09-01  

Identity

HGNC
LOCATION
7p15.1
LOCUSID
ALIAS
CRE-BPA,CREB-5,CREBPA
FUSION GENES

Other Information

Locus ID:

NCBI: 9586
MIM: 618262
HGNC: 16844
Ensembl: ENSG00000146592

Variants:

dbSNP: 9586
ClinVar: 9586
TCGA: ENSG00000146592
COSMIC: CREB5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000146592ENST00000357727Q02930
ENSG00000146592ENST00000396298Q02930
ENSG00000146592ENST00000396299Q02930
ENSG00000146592ENST00000396300Q02930
ENSG00000146592ENST00000409603Q02930
ENSG00000146592ENST00000424599H9KVC5
ENSG00000146592ENST00000426500C9JN33
ENSG00000146592ENST00000498316H0YFV2

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Huntington's diseaseKEGGko05016
Prostate cancerKEGGko05215
Huntington's diseaseKEGGhsa05016
Prostate cancerKEGGhsa05215
Vasopressin-regulated water reabsorptionKEGGko04962
Vasopressin-regulated water reabsorptionKEGGhsa04962
Cholinergic synapseKEGGhsa04725
Dopaminergic synapseKEGGko04728
Dopaminergic synapseKEGGhsa04728
Cocaine addictionKEGGhsa05030
Cocaine addictionKEGGko05030
Amphetamine addictionKEGGhsa05031
Amphetamine addictionKEGGko05031
AlcoholismKEGGhsa05034
AlcoholismKEGGko05034
Viral carcinogenesisKEGGhsa05203
Viral carcinogenesisKEGGko05203
PI3K-Akt signaling pathwayKEGGhsa04151
PI3K-Akt signaling pathwayKEGGko04151
Hepatitis BKEGGhsa05161
Insulin secretionKEGGhsa04911
Estrogen signaling pathwayKEGGhsa04915
Estrogen signaling pathwayKEGGko04915
TNF signaling pathwayKEGGhsa04668
TNF signaling pathwayKEGGko04668
Thyroid hormone synthesisKEGGhsa04918
Thyroid hormone synthesisKEGGko04918
Adrenergic signaling in cardiomyocytesKEGGhsa04261
Adrenergic signaling in cardiomyocytesKEGGko04261
cGMP-PKG signaling pathwayKEGGhsa04022
cGMP-PKG signaling pathwayKEGGko04022
AMPK signaling pathwayKEGGhsa04152
AMPK signaling pathwayKEGGko04152
cAMP signaling pathwayKEGGhsa04024
cAMP signaling pathwayKEGGko04024
Glucagon signaling pathwayKEGGhsa04922
Glucagon signaling pathwayKEGGko04922
Aldosterone synthesis and secretionKEGGhsa04925
Insulin resistanceKEGGhsa04931
Aldosterone synthesis and secretionKEGGko04925
Longevity regulating pathwayKEGGhsa04211

References

Pubmed IDYearTitleCitations
379960582024SPOP promotes CREB5 ubiquitination to inhibit MET signaling in liver cancer.0
384244072024Dysregulation of CREB5 Impairs Decidualization and Maternal-Fetal Interactions by Inhibiting Autophagy in Recurrent Spontaneous Abortion.0
385476572024Identification of CREB5 as a prognostic and immunotherapeutic biomarker in glioma through multi-omics pan-cancer analysis.0
385497172024Plasma microRNA-320c as a Potential Biomarker for the Severity of Knee Osteoarthritis and Regulates cAMP Responsive Element Binding Protein 5 (CREB5) in Chondrocytes.0
390150252024RGS1 and CREB5 are direct and common transcriptional targets of ZNF384-fusion proteins.1
379960582024SPOP promotes CREB5 ubiquitination to inhibit MET signaling in liver cancer.0
384244072024Dysregulation of CREB5 Impairs Decidualization and Maternal-Fetal Interactions by Inhibiting Autophagy in Recurrent Spontaneous Abortion.0
385476572024Identification of CREB5 as a prognostic and immunotherapeutic biomarker in glioma through multi-omics pan-cancer analysis.0
385497172024Plasma microRNA-320c as a Potential Biomarker for the Severity of Knee Osteoarthritis and Regulates cAMP Responsive Element Binding Protein 5 (CREB5) in Chondrocytes.0
390150252024RGS1 and CREB5 are direct and common transcriptional targets of ZNF384-fusion proteins.1
365650372023Long noncoding RNA SNHG4 promotes the malignant progression of hepatocellular carcinoma through the miR-211-5p/CREB5 axis.1
373371492023Regulon analysis identifies protective FXR and CREB5 in proximal tubules in early diabetic kidney disease.3
378168202023The ATF2/miR-3913-5p/CREB5 axis is involved in the cell proliferation and metastasis of colorectal cancer.0
365650372023Long noncoding RNA SNHG4 promotes the malignant progression of hepatocellular carcinoma through the miR-211-5p/CREB5 axis.1
373371492023Regulon analysis identifies protective FXR and CREB5 in proximal tubules in early diabetic kidney disease.3

Citation

Dessen P

CREB5 (cAMP responsive element binding protein 5)

Atlas Genet Cytogenet Oncol Haematol. 2014-09-01

Online version: http://atlasgeneticsoncology.org/gene/54898/gene-explorer/teaching-explorer/