Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 220213
MIM: 612022
HGNC: 27346
Ensembl: ENSG00000165312
Variants:
dbSNP: 220213
ClinVar: 220213
TCGA: ENSG00000165312
COSMIC: OTUD1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000165312 | ENST00000376495 | Q5VV17 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36640312 | 2023 | The deubiquitinase OTUD1 noncanonically suppresses Akt activation through its N-terminal intrinsically disordered region. | 3 |
| 37639212 | 2023 | The Deubiquitinase OTUD1 Suppresses Secretory Neutrophil Polarization And Ameliorates Immunopathology of Periodontitis. | 2 |
| 36640312 | 2023 | The deubiquitinase OTUD1 noncanonically suppresses Akt activation through its N-terminal intrinsically disordered region. | 3 |
| 37639212 | 2023 | The Deubiquitinase OTUD1 Suppresses Secretory Neutrophil Polarization And Ameliorates Immunopathology of Periodontitis. | 2 |
| 34826170 | 2022 | Melatonin induces apoptotic cell death through Bim stabilization by Sp1-mediated OTUD1 upregulation. | 7 |
| 35941131 | 2022 | OTUD1 deubiquitinase regulates NF-κB- and KEAP1-mediated inflammatory responses and reactive oxygen species-associated cell death pathways. | 12 |
| 36357400 | 2022 | The deubiquitinase OTUD1 regulates immunoglobulin production and proteasome inhibitor sensitivity in multiple myeloma. | 7 |
| 34826170 | 2022 | Melatonin induces apoptotic cell death through Bim stabilization by Sp1-mediated OTUD1 upregulation. | 7 |
| 35941131 | 2022 | OTUD1 deubiquitinase regulates NF-κB- and KEAP1-mediated inflammatory responses and reactive oxygen species-associated cell death pathways. | 12 |
| 36357400 | 2022 | The deubiquitinase OTUD1 regulates immunoglobulin production and proteasome inhibitor sensitivity in multiple myeloma. | 7 |
| 33393230 | 2021 | The deubiquitinase OTUD1 enhances iron transport and potentiates host antitumor immunity. | 60 |
| 33898171 | 2021 | OTUD1 Activates Caspase-Independent and Caspase-Dependent Apoptosis by Promoting AIF Nuclear Translocation and MCL1 Degradation. | 22 |
| 33393230 | 2021 | The deubiquitinase OTUD1 enhances iron transport and potentiates host antitumor immunity. | 60 |
| 33898171 | 2021 | OTUD1 Activates Caspase-Independent and Caspase-Dependent Apoptosis by Promoting AIF Nuclear Translocation and MCL1 Degradation. | 22 |
| 32075857 | 2020 | OTUD1 Negatively Regulates Type I IFN Induction by Disrupting Noncanonical Ubiquitination of IRF3. | 33 |
Citation
Dessen P
OTUD1 (OTU deubiquitinase 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-10-01
Online version: http://atlasgeneticsoncology.org/gene/54907/otud1-(otu-deubiquitinase-1)
