SP2 (Sp2 transcription factor)

2014-10-01  

Identity

HGNC
SP2
LOCATION
17q21.32
LOCUSID
6668
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 6668
MIM: 601801
HGNC: 11207
Ensembl: ENSG00000167182

Variants:

dbSNP: 6668
ClinVar: 6668
TCGA: ENSG00000167182
COSMIC: SP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000167182ENST00000376741Q02086
ENSG00000167182ENST00000613139Q9BRW5
ENSG00000167182ENST00000635868A0A1B0GTK3
ENSG00000167182ENST00000637314A0A1B0GVH1
ENSG00000167182ENST00000637943A0A1B0GV29
ENSG00000167182ENST00000642065A0A286YFJ7

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
349149642022Transcription factor Sp2 promotes TGFB-mediated interstitial cell osteogenic differentiation in bicuspid aortic valves through a SMAD-dependent pathway.6
349149642022Transcription factor Sp2 promotes TGFB-mediated interstitial cell osteogenic differentiation in bicuspid aortic valves through a SMAD-dependent pathway.6
346877962021Transcription Factor SP2 Regulates Ski-mediated Astrocyte Proliferation In Vitro.0
346877962021Transcription Factor SP2 Regulates Ski-mediated Astrocyte Proliferation In Vitro.0
321606552020Sp2 promotes invasion and metastasis of hepatocellular carcinoma by targeting TRIB3 protein.12
321606552020Sp2 promotes invasion and metastasis of hepatocellular carcinoma by targeting TRIB3 protein.12
271283722016Novel Mutation (Gly212Val) in the PS2 Gene Associated with Early-Onset Familial Alzheimer's Disease.2
272565742016Expression of human gene coding RORγT receptor depends on the Sp2 transcription factor.9
271283722016Novel Mutation (Gly212Val) in the PS2 Gene Associated with Early-Onset Familial Alzheimer's Disease.2
272565742016Expression of human gene coding RORγT receptor depends on the Sp2 transcription factor.9
264318792015O-GlcNAc modification of Sp3 and Sp4 transcription factors negatively regulates their transcriptional activities.6
264318792015O-GlcNAc modification of Sp3 and Sp4 transcription factors negatively regulates their transcriptional activities.6
246233142014miR-638 suppresses cell proliferation in gastric cancer by targeting Sp2.39
246233142014miR-638 suppresses cell proliferation in gastric cancer by targeting Sp2.39
194823582009Sp2 regulates interferon-gamma-mediated socs1 gene expression.4

Citation

Dessen P

SP2 (Sp2 transcription factor)

Atlas Genet Cytogenet Oncol Haematol. 2014-10-01

Online version: http://atlasgeneticsoncology.org/gene/54936/sp2-(sp2-transcription-factor)