Identity
HGNC
LOCATION
17q11.2
LOCUSID
ALIAS
DEEPEST,MAP126,hMAP126
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10615
MIM: 615562
HGNC: 13452
Ensembl: ENSG00000076382
Variants:
dbSNP: 10615
ClinVar: 10615
TCGA: ENSG00000076382
COSMIC: SPAG5
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37539742 | 2023 | SPAG5, the upstream protein of Wnt and the target of curcumin, inhibits hepatocellular carcinoma. | 2 |
| 37929348 | 2023 | SPAG5 promotes the proliferation, migration, invasion, and epithelial-mesenchymal transformation of colorectal cancer cells by activating the PI3K/AKT signaling pathway. | 2 |
| 37539742 | 2023 | SPAG5, the upstream protein of Wnt and the target of curcumin, inhibits hepatocellular carcinoma. | 2 |
| 37929348 | 2023 | SPAG5 promotes the proliferation, migration, invasion, and epithelial-mesenchymal transformation of colorectal cancer cells by activating the PI3K/AKT signaling pathway. | 2 |
| 35138218 | 2022 | Downregulation of sperm-associated antigen 5 inhibits melanoma progression by regulating forkhead box protein M1/A disintegrin and metalloproteinase 17/NOTCH1 signaling. | 2 |
| 35730922 | 2022 | SPAG5 as a novel biomarker and potential therapeutic target via regulating AKT pathway in multiple myeloma. | 2 |
| 35138218 | 2022 | Downregulation of sperm-associated antigen 5 inhibits melanoma progression by regulating forkhead box protein M1/A disintegrin and metalloproteinase 17/NOTCH1 signaling. | 2 |
| 35730922 | 2022 | SPAG5 as a novel biomarker and potential therapeutic target via regulating AKT pathway in multiple myeloma. | 2 |
| 34057242 | 2021 | MiR-133a-3p attenuates resistance of non-small cell lung cancer cells to gefitinib by targeting SPAG5. | 8 |
| 34903799 | 2021 | CircFOXM1 promotes proliferation and metastasis of hepatocellular carcinoma via regulating miR-1179/SPAG5 axis. | 4 |
| 34057242 | 2021 | MiR-133a-3p attenuates resistance of non-small cell lung cancer cells to gefitinib by targeting SPAG5. | 8 |
| 34903799 | 2021 | CircFOXM1 promotes proliferation and metastasis of hepatocellular carcinoma via regulating miR-1179/SPAG5 axis. | 4 |
| 31792998 | 2020 | MicroRNA-367-3p overexpression represses the proliferation and invasion of cervical cancer cells through downregulation of SPAG5-mediated Wnt/β-catenin signalling. | 5 |
| 31860771 | 2020 | Expression, immune infiltration and clinical significance of SPAG5 in hepatocellular carcinoma: A gene expression-based study. | 11 |
| 31957155 | 2020 | SPAG5-AS1 inhibited autophagy and aggravated apoptosis of podocytes via SPAG5/AKT/mTOR pathway. | 42 |
Citation
Dessen P
SPAG5 (sperm associated antigen 5)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/54948/spag5-(sperm-associated-antigen-5)
