Identity
HGNC
LOCATION
19q13.31
LOCUSID
ALIAS
HNA-2a,HNA2A,NB1,NB1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 57126
MIM: 162860
HGNC: 30072
Ensembl: ENSG00000204936
Variants:
dbSNP: 57126
ClinVar: 57126
TCGA: ENSG00000204936
COSMIC: CD177
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000204936 | ENST00000378012 | Q8N6Q3 |
| ENSG00000204936 | ENST00000607855 | A0A087X113 |
| ENSG00000204936 | ENST00000618265 | A0A087WVM2 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38474126 | 2024 | The CD177 c.1291A Allele Leads to a Loss of Membrane Expression and Mimics a CD177-Null Phenotype. | 1 |
| 38474126 | 2024 | The CD177 c.1291A Allele Leads to a Loss of Membrane Expression and Mimics a CD177-Null Phenotype. | 1 |
| 36352147 | 2023 | Diagnostic, prognostic, and immunological roles of CD177 in cervical cancer. | 1 |
| 36352147 | 2023 | Diagnostic, prognostic, and immunological roles of CD177 in cervical cancer. | 1 |
| 35063507 | 2022 | Competitively disrupting the neutrophil-specific receptor-autoantigen CD177:proteinase 3 membrane complex reduces anti-PR3 antibody-induced neutrophil activation. | 2 |
| 35063507 | 2022 | Competitively disrupting the neutrophil-specific receptor-autoantigen CD177:proteinase 3 membrane complex reduces anti-PR3 antibody-induced neutrophil activation. | 2 |
| 32531826 | 2021 | The neutrophil subset defined by CD177 expression is preferentially recruited to gingival crevicular fluid in periodontitis. | 11 |
| 33734454 | 2021 | Characterization of CD177-reactive iso- and auto-antibodies. | 3 |
| 34599187 | 2021 | CD177 modulates the function and homeostasis of tumor-infiltrating regulatory T cells. | 28 |
| 34879110 | 2021 | The neutrophil protein CD177 is a novel PDPN receptor that regulates human cancer-associated fibroblast physiology. | 7 |
| 32531826 | 2021 | The neutrophil subset defined by CD177 expression is preferentially recruited to gingival crevicular fluid in periodontitis. | 11 |
| 33734454 | 2021 | Characterization of CD177-reactive iso- and auto-antibodies. | 3 |
| 34599187 | 2021 | CD177 modulates the function and homeostasis of tumor-infiltrating regulatory T cells. | 28 |
| 34879110 | 2021 | The neutrophil protein CD177 is a novel PDPN receptor that regulates human cancer-associated fibroblast physiology. | 7 |
| 31777111 | 2020 | A novel nonsense mutation found in the CD177 gene of Thai individuals with the HNA-2 null phenotype. | 2 |
Citation
Dessen P
CD177 (CD177 molecule)
Atlas Genet Cytogenet Oncol Haematol. 2015-02-01
Online version: http://atlasgeneticsoncology.org/gene/54964/cd177-(cd177-molecule)
