SUSD6 (sushi domain containing 6)

2015-02-01  

Identity

HGNC
LOCATION
14q24.1
LOCUSID
ALIAS
DRAGO,KIAA0247
FUSION GENES

Other Information

Locus ID:

NCBI: 9766
MIM: 616761
HGNC: 19956
Ensembl: ENSG00000100647

Variants:

dbSNP: 9766
ClinVar: 9766
TCGA: ENSG00000100647
COSMIC: SUSD6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100647ENST00000342745Q92537

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
202366272010Characterization of SVEP1, KIAA, and SRPX2 in an in vitro cell culture model of endotoxemia.11
216196782011A predicted protein, KIAA0247, is a cell cycle modulator in colorectal cancer cells under 5-FU treatment.8
278934302016KIAA0247 suppresses the proliferation, angiogenesis and promote apoptosis of human glioma through inactivation of the AKT and Stat3 signaling pathway.8
246526522014DRAGO (KIAA0247), a new DNA damage-responsive, p53-inducible gene that cooperates with p53 as oncosuppressor. [Corrected].7
294517182018KIAA0247 inhibits growth, migration, invasion of non-small-cell lung cancer through regulating the Notch pathway.6

Citation

Dessen P

SUSD6 (sushi domain containing 6)

Atlas Genet Cytogenet Oncol Haematol. 2015-02-01

Online version: http://atlasgeneticsoncology.org/gene/54965/susd6-(sushi-domain-containing-6)