SLC39A10 (solute carrier family 39 member 10)

2015-02-01  

Identity

HGNC
LOCATION
2q32.3
LOCUSID
ALIAS
LZT-Hs2
FUSION GENES

Other Information

Locus ID:

NCBI: 57181
MIM: 608733
HGNC: 20861
Ensembl: ENSG00000196950

Variants:

dbSNP: 57181
ClinVar: 57181
TCGA: ENSG00000196950
COSMIC: SLC39A10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000196950ENST00000359634Q9ULF5
ENSG00000196950ENST00000359634A0A024R3W5
ENSG00000196950ENST00000409086Q9ULF5
ENSG00000196950ENST00000409086A0A024R3W5
ENSG00000196950ENST00000412905C9J0F5
ENSG00000196950ENST00000418005E7EV45
ENSG00000196950ENST00000430412F2Z341
ENSG00000196950ENST00000444421F2Z341
ENSG00000196950ENST00000458054E7ENT5

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsREACTOMER-HSA-425366
Metal ion SLC transportersREACTOMER-HSA-425410
Zinc transportersREACTOMER-HSA-435354
Zinc influx into cells by the SLC39 gene familyREACTOMER-HSA-442380

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
364095272023The bZIP transcription factor BATF3/ZIP-10 suppresses innate immunity by attenuating PMK-1/p38 signaling.1
364545092023Functional characterization of SLC39 family members ZIP5 and ZIP10 in overexpressing HEK293 cells reveals selective copper transport activity.4
375248742023SLC39A10 promotes malignant phenotypes of gastric cancer cells by activating the CK2-mediated MAPK/ERK and PI3K/AKT pathways.2
364095272023The bZIP transcription factor BATF3/ZIP-10 suppresses innate immunity by attenuating PMK-1/p38 signaling.1
364545092023Functional characterization of SLC39 family members ZIP5 and ZIP10 in overexpressing HEK293 cells reveals selective copper transport activity.4
375248742023SLC39A10 promotes malignant phenotypes of gastric cancer cells by activating the CK2-mediated MAPK/ERK and PI3K/AKT pathways.2
327972462021The ZIP6/ZIP10 heteromer is essential for the zinc-mediated trigger of mitosis.17
347067472021ZIP10 drives osteosarcoma proliferation and chemoresistance through ITGA10-mediated activation of the PI3K/AKT pathway.30
327972462021The ZIP6/ZIP10 heteromer is essential for the zinc-mediated trigger of mitosis.17
347067472021ZIP10 drives osteosarcoma proliferation and chemoresistance through ITGA10-mediated activation of the PI3K/AKT pathway.30
318754922020Possible involvement of zinc transporter ZIP10 in atopic dermatitis.3
318754922020Possible involvement of zinc transporter ZIP10 in atopic dermatitis.3
305206572019Cloning, function, and localization of human, canine, and Drosophila ZIP10 (SLC39A10), a Zn(2+) transporter.7
305206572019Cloning, function, and localization of human, canine, and Drosophila ZIP10 (SLC39A10), a Zn(2+) transporter.7
291804212017Metal transporter Slc39a10 regulates susceptibility to inflammatory stimuli by controlling macrophage survival.27

Citation

Dessen P

SLC39A10 (solute carrier family 39 member 10)

Atlas Genet Cytogenet Oncol Haematol. 2015-02-01

Online version: http://atlasgeneticsoncology.org/gene/54968/slc39a10-(solute-carrier-family-39-member-10)