Identity
HGNC
LOCATION
19q13.42
LOCUSID
ALIAS
CLR19.3,FCAS2,NALP12,PAN6,PYPAF7,RNO,RNO2
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 91662
MIM: 609648
HGNC: 22938
Ensembl: ENSG00000142405
Variants:
dbSNP: 91662
ClinVar: 91662
TCGA: ENSG00000142405
COSMIC: NLRP12
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| NOD-like receptor signaling pathway | KEGG | ko04621 |
| NOD-like receptor signaling pathway | KEGG | hsa04621 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37976229 | 2024 | NLRP12 Senses the SARS-CoV-2 Membrane Protein and Promotes an Inflammatory Response. | 1 |
| 38177227 | 2024 | The contributions of deleterious rare alleles in NLRP12 and inflammasome-related genes to polymyalgia rheumatica. | 1 |
| 38261657 | 2024 | NLRP12 interacts with NLRP3 to block the activation of the human NLRP3 inflammasome. | 3 |
| 37976229 | 2024 | NLRP12 Senses the SARS-CoV-2 Membrane Protein and Promotes an Inflammatory Response. | 1 |
| 38177227 | 2024 | The contributions of deleterious rare alleles in NLRP12 and inflammasome-related genes to polymyalgia rheumatica. | 1 |
| 38261657 | 2024 | NLRP12 interacts with NLRP3 to block the activation of the human NLRP3 inflammasome. | 3 |
| 36599143 | 2023 | High expression of NLRP12 predicts poor prognosis in patients with intracranial glioma. | 0 |
| 37572944 | 2023 | The role of NLRP12 in inflammatory diseases. | 1 |
| 37581937 | 2023 | NLRP12 downregulates the Wnt/β-catenin pathway via interaction with STK38 to suppress colorectal cancer. | 6 |
| 37877365 | 2023 | NLRP12-associated autoinflammatory disease: much more than the FCAS phenotype. | 0 |
| 38123482 | 2023 | NLRP12-associated autoinflammatory disease in Chinese adult patients: a single-centre study. | 0 |
| 36599143 | 2023 | High expression of NLRP12 predicts poor prognosis in patients with intracranial glioma. | 0 |
| 37572944 | 2023 | The role of NLRP12 in inflammatory diseases. | 1 |
| 37581937 | 2023 | NLRP12 downregulates the Wnt/β-catenin pathway via interaction with STK38 to suppress colorectal cancer. | 6 |
| 37877365 | 2023 | NLRP12-associated autoinflammatory disease: much more than the FCAS phenotype. | 0 |
Citation
Dessen P
NLRP12 (NLR family pyrin domain containing 12)
Atlas Genet Cytogenet Oncol Haematol. 2015-02-01
Online version: http://atlasgeneticsoncology.org/gene/54969/nlrp12-(nlr-family-pyrin-domain-containing-12)
