ARL5A (ADP ribosylation factor like GTPase 5A)

2015-02-01  

Identity

HGNC
ARL5A
LOCATION
2q23.3
LOCUSID
26225
ALIAS
ARFLP5,ARL5
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 26225
MIM: 608960
HGNC: 696
Ensembl: ENSG00000162980

Variants:

dbSNP: 26225
ClinVar: 26225
TCGA: ENSG00000162980
COSMIC: ARL5A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000162980ENST00000295087Q9Y689
ENSG00000162980ENST00000428992Q9Y689
ENSG00000162980ENST00000446896Q9Y689
ENSG00000162980ENST00000458140F8WER2

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
243272742014microRNA-202-3p inhibits cell proliferation by targeting ADP-ribosylation factor-like 5A in human colorectal carcinoma.32
124149902002A developmentally regulated ARF-like 5 protein (ARL5), localized to nuclei and nucleoli, interacts with heterochromatin protein 1.11
1589670520052.0 A crystal structure of human ARL5-GDP3'P, a novel member of the small GTP-binding proteins.2
304782712018Amino acids stimulate the endosome-to-Golgi trafficking through Ragulator and small GTPase Arl5.1
315756032019ARFRP1 functions upstream of ARL1 and ARL5 to coordinate recruitment of distinct tethering factors to the trans-Golgi network.1

Citation

Dessen P

ARL5A (ADP ribosylation factor like GTPase 5A)

Atlas Genet Cytogenet Oncol Haematol. 2015-02-01

Online version: http://atlasgeneticsoncology.org/gene/54971/arl5a-(adp-ribosylation-factor-like-gtpase-5a)