STOM (stomatin)

2015-02-01  

Identity

HGNC
LOCATION
9q33.2
LOCUSID
ALIAS
BND7,EPB7,EPB72
FUSION GENES

Other Information

Locus ID:

NCBI: 2040
MIM: 133090
HGNC: 3383
Ensembl: ENSG00000148175

Variants:

dbSNP: 2040
ClinVar: 2040
TCGA: ENSG00000148175
COSMIC: STOM

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000148175ENST00000286713P27105
ENSG00000148175ENST00000286713A0A024R882
ENSG00000148175ENST00000347359P27105
ENSG00000148175ENST00000538954F8VSL7

Expression (GTEx)

0
50
100
150
200
250
300
350
400
450
500

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Transmembrane transport of small moleculesREACTOMER-HSA-382551
Ion channel transportREACTOMER-HSA-983712
Stimuli-sensing channelsREACTOMER-HSA-2672351
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
381856152024Stomatin promotes neutrophil degranulation and vascular leakage in the early stage after severe burn via enhancement of the intracellular binding of neutrophil primary granules to F-actin.1
381856152024Stomatin promotes neutrophil degranulation and vascular leakage in the early stage after severe burn via enhancement of the intracellular binding of neutrophil primary granules to F-actin.1
360126672022Mechanosensitive Pannexin 1 Activity Is Modulated by Stomatin in Human Red Blood Cells.2
360126672022Mechanosensitive Pannexin 1 Activity Is Modulated by Stomatin in Human Red Blood Cells.2
329512592021Stomatin is highly expressed in exosomes of different origin and is a promising candidate as an exosomal marker.10
337579772021Stomatin-Mediated Inhibition of the Akt Signaling Axis Suppresses Tumor Growth.2
344202532021Cell-to-cell contact-mediated regulation of tumor behavior in the tumor microenvironment.16
329512592021Stomatin is highly expressed in exosomes of different origin and is a promising candidate as an exosomal marker.10
337579772021Stomatin-Mediated Inhibition of the Akt Signaling Axis Suppresses Tumor Growth.2
344202532021Cell-to-cell contact-mediated regulation of tumor behavior in the tumor microenvironment.16
323161892020The Lipid Raft Component Stomatin Interacts with the Na(+) Taurocholate Cotransporting Polypeptide (NTCP) and Modulates Bile Salt Uptake.1
323161892020The Lipid Raft Component Stomatin Interacts with the Na(+) Taurocholate Cotransporting Polypeptide (NTCP) and Modulates Bile Salt Uptake.1
276638612017Lipid raft-associated stomatin enhances cell fusion.15
283873072017Stomatin modulates the activity of the Anion Exchanger 1 (AE1, SLC4A1).18
285750932017Structure-function analysis of human stomatin: A mutation study.21

Citation

Dessen P

STOM (stomatin)

Atlas Genet Cytogenet Oncol Haematol. 2015-02-01

Online version: http://atlasgeneticsoncology.org/gene/54975/stom-(stomatin)