Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 100288687
MIM: 606009
HGNC: 50800
Ensembl: ENSG00000260596
Variants:
dbSNP: 100288687
ClinVar: 100288687
TCGA: ENSG00000260596
COSMIC: DUX4
RNA/Proteins
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38451221 | 2024 | DUX4-induced HSATII transcription causes KDM2A/B-PRC1 nuclear foci and impairs DNA damage response. | 0 |
| 38542301 | 2024 | The DUX4-HIF1α Axis in Murine and Human Muscle Cells: A Link More Complex Than Expected. | 0 |
| 38809976 | 2024 | DNMT3B splicing dysregulation mediated by SMCHD1 loss contributes to DUX4 overexpression and FSHD pathogenesis. | 0 |
| 38451221 | 2024 | DUX4-induced HSATII transcription causes KDM2A/B-PRC1 nuclear foci and impairs DNA damage response. | 0 |
| 38542301 | 2024 | The DUX4-HIF1α Axis in Murine and Human Muscle Cells: A Link More Complex Than Expected. | 0 |
| 38809976 | 2024 | DNMT3B splicing dysregulation mediated by SMCHD1 loss contributes to DUX4 overexpression and FSHD pathogenesis. | 0 |
| 36728804 | 2023 | Human DUX4 and porcine DUXC activate similar early embryonic programs in pig muscle cells: implications for preclinical models of FSHD. | 3 |
| 36800423 | 2023 | DUX4 double whammy: The transcription factor that causes a rare muscular dystrophy also kills the precursors of the human nose. | 4 |
| 37021550 | 2023 | WDR5 is required for DUX4 expression and its pathological effects in FSHD muscular dystrophy. | 1 |
| 37092726 | 2023 | Human DUX4 and mouse Dux interact with STAT1 and broadly inhibit interferon-stimulated gene induction. | 6 |
| 37186119 | 2023 | Post-Translational Modifications of the DUX4 Protein Impact Toxic Function in FSHD Cell Models. | 1 |
| 37298453 | 2023 | Influence of DUX4 Expression in Facioscapulohumeral Muscular Dystrophy and Possible Treatments. | 3 |
| 37314931 | 2023 | Compromised nonsense-mediated RNA decay results in truncated RNA-binding protein production upon DUX4 expression. | 6 |
| 37691147 | 2023 | DUX4 expression in cancer induces a metastable early embryonic totipotent program. | 0 |
| 37703175 | 2023 | MATR3 is an endogenous inhibitor of DUX4 in FSHD muscular dystrophy. | 3 |
Citation
Dessen P
DUX4 (double homeobox 4)
Atlas Genet Cytogenet Oncol Haematol. 2015-02-01
Online version: http://atlasgeneticsoncology.org/gene/54984
