SLC39A9 (solute carrier family 39 member 9)

2015-02-01  

Identity

HGNC
LOCATION
14q24.1
LOCUSID
ALIAS
ZIP-9,ZIP9
FUSION GENES

Other Information

Locus ID:

NCBI: 55334
HGNC: 20182
Ensembl: ENSG00000029364

Variants:

dbSNP: 55334
ClinVar: 55334
TCGA: ENSG00000029364
COSMIC: SLC39A9

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000029364ENST00000031146M0QX28
ENSG00000029364ENST00000336643Q9NUM3
ENSG00000029364ENST00000336643C4N9M8
ENSG00000029364ENST00000555840Q9NUM3
ENSG00000029364ENST00000555840C4N9M8
ENSG00000029364ENST00000556605Q9NUM3
ENSG00000029364ENST00000557046Q9NUM3
ENSG00000029364ENST00000628474A0A0D9SFA2

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
345554252021Androgens promote vascular endothelial cell proliferation through activation of a ZIP9-dependent inhibitory G protein/PI3K-Akt/Erk/cyclin D1 pathway.0
347068622021ZIP9 Is a Druggable Determinant of Sex Differences in Melanoma.11
345554252021Androgens promote vascular endothelial cell proliferation through activation of a ZIP9-dependent inhibitory G protein/PI3K-Akt/Erk/cyclin D1 pathway.0
347068622021ZIP9 Is a Druggable Determinant of Sex Differences in Melanoma.11
312545152020Genome-Wide Analysis Reveals Zinc Transporter ZIP9 Regulated by DNA Methylation Promotes Radiation-Induced Skin Fibrosis via the TGF-β Signaling Pathway.10
315066052020Androgen dihydrotestosterone (DHT) promotes the bladder cancer nuclear AR-negative cell invasion via a newly identified membrane androgen receptor (mAR-SLC39A9)-mediated Gαi protein/MAPK/MMP9 intracellular signaling.15
312545152020Genome-Wide Analysis Reveals Zinc Transporter ZIP9 Regulated by DNA Methylation Promotes Radiation-Induced Skin Fibrosis via the TGF-β Signaling Pathway.10
315066052020Androgen dihydrotestosterone (DHT) promotes the bladder cancer nuclear AR-negative cell invasion via a newly identified membrane androgen receptor (mAR-SLC39A9)-mediated Gαi protein/MAPK/MMP9 intracellular signaling.15
307079082019Membrane androgen receptors (OXER1, GPRC6A AND ZIP9) in prostate and breast cancer: A comparative study of their expression.21
307079082019Membrane androgen receptors (OXER1, GPRC6A AND ZIP9) in prostate and breast cancer: A comparative study of their expression.21
302624332018ZIP9 but not the androgen receptor mediates testosterone-induced migratory activity of metastatic prostate cancer cells.16
302624332018ZIP9 but not the androgen receptor mediates testosterone-induced migratory activity of metastatic prostate cancer cells.16
282197372017Membrane androgen receptor characteristics of human ZIP9 (SLC39A) zinc transporter in prostate cancer cells: Androgen-specific activation and involvement of an inhibitory G protein in zinc and MAP kinase signaling.21
289433992017Testosterone/bicalutamide antagonism at the predicted extracellular androgen binding site of ZIP9.11
282197372017Membrane androgen receptor characteristics of human ZIP9 (SLC39A) zinc transporter in prostate cancer cells: Androgen-specific activation and involvement of an inhibitory G protein in zinc and MAP kinase signaling.21

Citation

Dessen P

SLC39A9 (solute carrier family 39 member 9)

Atlas Genet Cytogenet Oncol Haematol. 2015-02-01

Online version: http://atlasgeneticsoncology.org/gene/54987/slc39a9-(solute-carrier-family-39-member-9)