Identity
HGNC
LOCATION
13q14.3
LOCUSID
ALIAS
PROF,WDF2,ZFYVE22
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 115825
MIM: 610418
HGNC: 20482
Ensembl: ENSG00000139668
Variants:
dbSNP: 115825
ClinVar: 115825
TCGA: ENSG00000139668
COSMIC: WDFY2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000139668 | ENST00000298125 | Q96P53 |
| ENSG00000139668 | ENST00000612477 | A0A087WZX3 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36780172 | 2023 | Circ_0115118 regulates endometrial functions through the miR-138-1-3p/WDFY2 axis in patients with PCOS†. | 1 |
| 36780172 | 2023 | Circ_0115118 regulates endometrial functions through the miR-138-1-3p/WDFY2 axis in patients with PCOS†. | 1 |
| 31253801 | 2019 | WDFY2 restrains matrix metalloproteinase secretion and cell invasion by controlling VAMP3-dependent recycling. | 20 |
| 31789342 | 2019 | P63 modulates the expression of the WDFY2 gene which is implicated in cancer regulation and limb development. | 4 |
| 31253801 | 2019 | WDFY2 restrains matrix metalloproteinase secretion and cell invasion by controlling VAMP3-dependent recycling. | 20 |
| 31789342 | 2019 | P63 modulates the expression of the WDFY2 gene which is implicated in cancer regulation and limb development. | 4 |
| 28653900 | 2017 | Overexpression of WDFY2 inhibits prostate cancer cell growth and migration via inactivation of Akt pathway. | 9 |
| 28653900 | 2017 | Overexpression of WDFY2 inhibits prostate cancer cell growth and migration via inactivation of Akt pathway. | 9 |
| 24675677 | 2014 | CDKN2D-WDFY2 is a cancer-specific fusion gene recurrent in high-grade serous ovarian carcinoma. | 25 |
| 24675677 | 2014 | CDKN2D-WDFY2 is a cancer-specific fusion gene recurrent in high-grade serous ovarian carcinoma. | 25 |
| 17313651 | 2007 | WD-repeat-propeller-FYVE protein, ProF, binds VAMP2 and protein kinase Czeta. | 13 |
| 17313651 | 2007 | WD-repeat-propeller-FYVE protein, ProF, binds VAMP2 and protein kinase Czeta. | 13 |
| 16792529 | 2006 | A WD-FYVE protein binds to the kinases Akt and PKCzeta/lambda. | 19 |
| 16873553 | 2006 | The WD40 and FYVE domain containing protein 2 defines a class of early endosomes necessary for endocytosis. | 31 |
| 16792529 | 2006 | A WD-FYVE protein binds to the kinases Akt and PKCzeta/lambda. | 19 |
Citation
Dessen P
WDFY2 (WD repeat and FYVE domain containing 2)
Atlas Genet Cytogenet Oncol Haematol. 2015-02-01
Online version: http://atlasgeneticsoncology.org/gene/55005/wdfy2-(wd-repeat-and-fyve-domain-containing-2)
