Identity
HGNC
LOCATION
4p15.32
LOCUSID
ALIAS
FBL4,FBL5,FLR1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 26234
MIM: 605655
HGNC: 13602
Ensembl: ENSG00000118564
Variants:
dbSNP: 26234
ClinVar: 26234
TCGA: ENSG00000118564
COSMIC: FBXL5
RNA/Proteins
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37093682 | 2023 | Loss of F-Box and Leucine Rich Repeat Protein 5 (FBXL5) Expression Is Associated With Poor Survival in Patients With Hepatocellular Carcinoma After Curative Resection: A Two-institute Study. | 0 |
| 37743009 | 2023 | FBXL5 promotes lipid accumulation in alcoholic fatty liver disease by promoting the ubiquitination and degradation of TFEB. | 0 |
| 37093682 | 2023 | Loss of F-Box and Leucine Rich Repeat Protein 5 (FBXL5) Expression Is Associated With Poor Survival in Patients With Hepatocellular Carcinoma After Curative Resection: A Two-institute Study. | 0 |
| 37743009 | 2023 | FBXL5 promotes lipid accumulation in alcoholic fatty liver disease by promoting the ubiquitination and degradation of TFEB. | 0 |
| 33735560 | 2021 | Ferroportin and FBXL5 as Prognostic Markers in Advanced Stage Clear Cell Renal Cell Carcinoma. | 2 |
| 33735560 | 2021 | Ferroportin and FBXL5 as Prognostic Markers in Advanced Stage Clear Cell Renal Cell Carcinoma. | 2 |
| 32126207 | 2020 | FBXL5 Regulates IRP2 Stability in Iron Homeostasis via an Oxygen-Responsive [2Fe2S] Cluster. | 49 |
| 32126207 | 2020 | FBXL5 Regulates IRP2 Stability in Iron Homeostasis via an Oxygen-Responsive [2Fe2S] Cluster. | 49 |
| 30877170 | 2019 | Disruption of FBXL5-mediated cellular iron homeostasis promotes liver carcinogenesis. | 25 |
| 31229404 | 2019 | An Oxygen-Dependent Interaction between FBXL5 and the CIA-Targeting Complex Regulates Iron Homeostasis. | 13 |
| 30877170 | 2019 | Disruption of FBXL5-mediated cellular iron homeostasis promotes liver carcinogenesis. | 25 |
| 31229404 | 2019 | An Oxygen-Dependent Interaction between FBXL5 and the CIA-Targeting Complex Regulates Iron Homeostasis. | 13 |
| 30219228 | 2018 | miR-1306-3p targets FBXL5 to promote metastasis of hepatocellular carcinoma through suppressing snail degradation. | 19 |
| 30257389 | 2018 | F-box and leucine-rich repeat protein 5 promotes colon cancer progression by modulating PTEN/PI3K/AKT signaling pathway. | 13 |
| 30219228 | 2018 | miR-1306-3p targets FBXL5 to promote metastasis of hepatocellular carcinoma through suppressing snail degradation. | 19 |
Citation
Dessen P
FBXL5 (F-box and leucine rich repeat protein 5)
Atlas Genet Cytogenet Oncol Haematol. 2015-02-01
Online version: http://atlasgeneticsoncology.org/gene/55008/fbxl5-(f-box-and-leucine-rich-repeat-protein-5)
