ARHGAP36 (Rho GTPase activating protein 36)

2015-02-01  

Identity

HGNC
ARHGAP36
LOCATION
Xq26.1
LOCUSID
158763
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 158763
MIM: 300937
HGNC: 26388
Ensembl: ENSG00000147256

Variants:

dbSNP: 158763
ClinVar: 158763
TCGA: ENSG00000147256
COSMIC: ARHGAP36

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000147256ENST00000276211Q6ZRI8
ENSG00000147256ENST00000370921Q6ZRI8
ENSG00000147256ENST00000370922Q6ZRI8
ENSG00000147256ENST00000412432Q6ZRI8
ENSG00000147256ENST00000412432A0A2X0TVT1
ENSG00000147256ENST00000423277X6RIA0
ENSG00000147256ENST00000639280Q6ZRI8

Expression (GTEx)

0
50
100
150
200
250
300
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
Rho GTPase cycleREACTOMER-HSA-194840

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
hypothalamus
thyroid gland
parathyroid gland
adrenal gland
pituitary gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
339999592021Structure-activity mapping of ARHGAP36 reveals regulatory roles for its GAP homology and C-terminal domains.2
339999592021Structure-activity mapping of ARHGAP36 reveals regulatory roles for its GAP homology and C-terminal domains.2
269113742016Cdc42 and Rac1 activity is reduced in human pheochromocytoma and correlates with FARP1 and ARHGEF1 expression.16
277134252016Bimodal antagonism of PKA signalling by ARHGAP36.20
269113742016Cdc42 and Rac1 activity is reduced in human pheochromocytoma and correlates with FARP1 and ARHGEF1 expression.16
277134252016Bimodal antagonism of PKA signalling by ARHGAP36.20
250242292014Arhgap36-dependent activation of Gli transcription factors.24
250242292014Arhgap36-dependent activation of Gli transcription factors.24
250242292014Arhgap36-dependent activation of Gli transcription factors.24
250242292014Arhgap36-dependent activation of Gli transcription factors.24

Citation

Dessen P

ARHGAP36 (Rho GTPase activating protein 36)

Atlas Genet Cytogenet Oncol Haematol. 2015-02-01

Online version: http://atlasgeneticsoncology.org/gene/55013/favicon/gene-fusions/humanGenome