USP20 (ubiquitin specific peptidase 20)

2015-02-01  

Identity

HGNC
LOCATION
9q34.11
LOCUSID
ALIAS
LSFR3A,VDU2,hVDU2
FUSION GENES

Other Information

Locus ID:

NCBI: 10868
MIM: 615143
HGNC: 12619
Ensembl: ENSG00000136878

Variants:

dbSNP: 10868
ClinVar: 10868
TCGA: ENSG00000136878
COSMIC: USP20

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000136878ENST00000315480Q9Y2K6
ENSG00000136878ENST00000358355Q9Y2K6
ENSG00000136878ENST00000372429Q9Y2K6

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
DeubiquitinationREACTOMER-HSA-5688426
Ub-specific processing proteasesREACTOMER-HSA-5689880

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
373115342023Phosphorylation of USP20 on Ser334 by IRAK1 promotes IL-1β-evoked signaling in vascular smooth muscle cells and vascular inflammation.1
373115342023Phosphorylation of USP20 on Ser334 by IRAK1 promotes IL-1β-evoked signaling in vascular smooth muscle cells and vascular inflammation.1
335297622021Expression, purification and characterization of the second DUSP domain of deubiquitinase USP20/VDU2.0
337926132021Deubiquitinases USP20/33 promote the biogenesis of tail-anchored membrane proteins.12
335297622021Expression, purification and characterization of the second DUSP domain of deubiquitinase USP20/VDU2.0
337926132021Deubiquitinases USP20/33 promote the biogenesis of tail-anchored membrane proteins.12
323541172020The Deubiquitinating Enzyme USP20 Regulates the TNFα-Induced NF-κB Signaling Pathway through Stabilization of p62.10
329435752020Deubiquitinase USP20 promotes breast cancer metastasis by stabilizing SNAI2.28
323541172020The Deubiquitinating Enzyme USP20 Regulates the TNFα-Induced NF-κB Signaling Pathway through Stabilization of p62.10
329435752020Deubiquitinase USP20 promotes breast cancer metastasis by stabilizing SNAI2.28
312787842019Structural and functional studies of USP20 ZnF-UBP domain by NMR.5
312787842019Structural and functional studies of USP20 ZnF-UBP domain by NMR.5
294870852018The deubiquitinating enzyme USP20 stabilizes ULK1 and promotes autophagy initiation.29
298671302018USP20 positively regulates tumorigenesis and chemoresistance through β-catenin stabilization.38
294870852018The deubiquitinating enzyme USP20 stabilizes ULK1 and promotes autophagy initiation.29

Citation

Dessen P

USP20 (ubiquitin specific peptidase 20)

Atlas Genet Cytogenet Oncol Haematol. 2015-02-01

Online version: http://atlasgeneticsoncology.org/gene/55017/usp20-(ubiquitin-specific-peptidase-20)