Identity
HGNC
LOCATION
15q15.1
LOCUSID
ALIAS
C15orf23,HSD11,ROCHIS,SKAP,TRAF4AF1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 90417
MIM: 614718
HGNC: 30767
Ensembl: ENSG00000128944
Variants:
dbSNP: 90417
ClinVar: 90417
TCGA: ENSG00000128944
COSMIC: KNSTRN
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34554241 | 2022 | SKAP interacts with Aurora B to guide end-on capture of spindle microtubules via phase separation. | 2 |
| 35201967 | 2022 | Phosphorylation of small kinetochore-associated protein induced by GSK3β promotes cell migration and invasion in esophageal cancer. | 1 |
| 34554241 | 2022 | SKAP interacts with Aurora B to guide end-on capture of spindle microtubules via phase separation. | 2 |
| 35201967 | 2022 | Phosphorylation of small kinetochore-associated protein induced by GSK3β promotes cell migration and invasion in esophageal cancer. | 1 |
| 33452459 | 2021 | KNSTRN promotes tumorigenesis and gemcitabine resistance by activating AKT in bladder cancer. | 22 |
| 33510346 | 2021 | Src-mediated tyrosine phosphorylation of PRC1 and kinastrin/SKAP on the mitotic spindle. | 0 |
| 33452459 | 2021 | KNSTRN promotes tumorigenesis and gemcitabine resistance by activating AKT in bladder cancer. | 22 |
| 33510346 | 2021 | Src-mediated tyrosine phosphorylation of PRC1 and kinastrin/SKAP on the mitotic spindle. | 0 |
| 30972880 | 2019 | Somatic mutations in kinetochore gene KNSTRN are associated with basal proliferating actinic keratoses and cutaneous squamous cell carcinoma. | 7 |
| 30972880 | 2019 | Somatic mutations in kinetochore gene KNSTRN are associated with basal proliferating actinic keratoses and cutaneous squamous cell carcinoma. | 7 |
| 28751710 | 2017 | Aurora-B kinase pathway controls the lateral to end-on conversion of kinetochore-microtubule attachments in human cells. | 41 |
| 28841134 | 2017 | Astrin-SKAP complex reconstitution reveals its kinetochore interaction with microtubule-bound Ndc80. | 25 |
| 28751710 | 2017 | Aurora-B kinase pathway controls the lateral to end-on conversion of kinetochore-microtubule attachments in human cells. | 41 |
| 28841134 | 2017 | Astrin-SKAP complex reconstitution reveals its kinetochore interaction with microtubule-bound Ndc80. | 25 |
| 26433880 | 2016 | Absence of KNSTRN Mutation, a Cutaneous Squamous Carcinoma-Specific Mutation, in Other Solid Tumors and Leukemias. | 4 |
Citation
Dessen P
KNSTRN (kinetochore localized astrin (SPAG5) binding protein)
Atlas Genet Cytogenet Oncol Haematol. 2015-02-01
Online version: http://atlasgeneticsoncology.org/gene/55018
