KCTD10 (potassium channel tetramerization domain containing 10)

2015-02-01  

Identity

HGNC
LOCATION
12q24.11
LOCUSID
ALIAS
BTBD28,MSTP028,ULRO61,hBACURD3
FUSION GENES

Other Information

Locus ID:

NCBI: 83892
MIM: 613421
HGNC: 23236
Ensembl: ENSG00000110906

Variants:

dbSNP: 83892
ClinVar: 83892
TCGA: ENSG00000110906
COSMIC: KCTD10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000110906ENST00000228495Q9H3F6
ENSG00000110906ENST00000228495A0A024RBJ2
ENSG00000110906ENST00000440541F8W8I7
ENSG00000110906ENST00000535546F5GWK6
ENSG00000110906ENST00000537165S4R3L9
ENSG00000110906ENST00000540089B3KVY5
ENSG00000110906ENST00000540355F5GY15
ENSG00000110906ENST00000540411F5GWA4
ENSG00000110906ENST00000541077S4R3Y7
ENSG00000110906ENST00000542262F5H6V0
ENSG00000110906ENST00000542858F5H497
ENSG00000110906ENST00000542954F5H268

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
389590432024The CRL3(KCTD10) ubiquitin ligase-USP18 axis coordinately regulates cystine uptake and ferroptosis by modulating SLC7A11.0
389590432024The CRL3(KCTD10) ubiquitin ligase-USP18 axis coordinately regulates cystine uptake and ferroptosis by modulating SLC7A11.0
305159332019Cullin-3/KCTD10 E3 complex is essential for Rac1 activation through RhoB degradation in human epidermal growth factor receptor 2-positive breast cancer cells.23
312808632019Cullin-3/KCTD10 complex is essential for K27-polyubiquitination of EIF3D in human hepatocellular carcinoma HepG2 cells.7
315830322019Haplotypes of HTRA1 rs1120638, TIMP3 rs9621532, VEGFA rs833068, CFI rs10033900, ERCC6 rs3793784, and KCTD10 rs56209061 Gene Polymorphisms in Age-Related Macular Degeneration.7
305159332019Cullin-3/KCTD10 E3 complex is essential for Rac1 activation through RhoB degradation in human epidermal growth factor receptor 2-positive breast cancer cells.23
312808632019Cullin-3/KCTD10 complex is essential for K27-polyubiquitination of EIF3D in human hepatocellular carcinoma HepG2 cells.7
315830322019Haplotypes of HTRA1 rs1120638, TIMP3 rs9621532, VEGFA rs833068, CFI rs10033900, ERCC6 rs3793784, and KCTD10 rs56209061 Gene Polymorphisms in Age-Related Macular Degeneration.7
293582112018The Cullin-3-Rbx1-KCTD10 complex controls endothelial barrier function via K63 ubiquitination of RhoB.28
304048372018Cullin-3-KCTD10-mediated CEP97 degradation promotes primary cilium formation.21
293582112018The Cullin-3-Rbx1-KCTD10 complex controls endothelial barrier function via K63 ubiquitination of RhoB.28
304048372018Cullin-3-KCTD10-mediated CEP97 degradation promotes primary cilium formation.21
277162952016Association of KCTD10, MVK, and MMAB polymorphisms with dyslipidemia and coronary heart disease in Han Chinese population.7
277162952016Association of KCTD10, MVK, and MMAB polymorphisms with dyslipidemia and coronary heart disease in Han Chinese population.7
239773942013Gene expression network analysis of ETV1 reveals KCTD10 as a novel prognostic biomarker in gastrointestinal stromal tumor.16

Citation

Dessen P

KCTD10 (potassium channel tetramerization domain containing 10)

Atlas Genet Cytogenet Oncol Haematol. 2015-02-01

Online version: http://atlasgeneticsoncology.org/gene/55029/kctd10-(potassium-channel-tetramerization-domain-containing-10)