CSPP1 (centrosome and spindle pole associated protein 1)

2015-02-01 Affiliation

Identity

HGNC

CSPP1

LOCATION

8q13.1

LOCUSID

79848

ALIAS

CSPP,CSPP-L,JBTS21

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 79848
MIM: 611654
HGNC: 26193
Ensembl: ENSG00000104218

Variants:

dbSNP: 79848
ClinVar: 79848
TCGA: ENSG00000104218
COSMIC: CSPP1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000104218	ENST00000262210	Q1MSJ5
ENSG00000104218	ENST00000519163	F2Z2M5
ENSG00000104218	ENST00000519668	Q1MSJ5
ENSG00000104218	ENST00000519701	E5RGA5
ENSG00000104218	ENST00000521919	E5RI67

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
36752787	2023	CSPP1 stabilizes growing microtubule ends and damaged lattices from the luminal side.	7
36752787	2023	CSPP1 stabilizes growing microtubule ends and damaged lattices from the luminal side.	7
35713481	2022	Circle RNA circCSPP1 promotes human osteosarcoma cell proliferation and increases glucose metabolism by suppressing miR-200c maturation.	1
35713481	2022	Circle RNA circCSPP1 promotes human osteosarcoma cell proliferation and increases glucose metabolism by suppressing miR-200c maturation.	1
32495924	2020	Roles of circ-CSPP1 on the proliferation and metastasis of glioma cancer.	4
32495924	2020	Roles of circ-CSPP1 on the proliferation and metastasis of glioma cancer.	4
30965236	2019	circ-CSPP1 promotes proliferation, invasion and migration of ovarian cancer cells by acting as a miR-1236-3p sponge.	37
30965236	2019	circ-CSPP1 promotes proliferation, invasion and migration of ovarian cancer cells by acting as a miR-1236-3p sponge.	37
26241740	2015	CSPP-L Associates with the Desmosome of Polarized Epithelial Cells and Is Required for Normal Spheroid Formation.	8
26378239	2015	Mitotic Protein CSPP1 Interacts with CENP-H Protein to Coordinate Accurate Chromosome Oscillation in Mitosis.	12
26241740	2015	CSPP-L Associates with the Desmosome of Polarized Epithelial Cells and Is Required for Normal Spheroid Formation.	8
26378239	2015	Mitotic Protein CSPP1 Interacts with CENP-H Protein to Coordinate Accurate Chromosome Oscillation in Mitosis.	12
24360803	2014	Mutations in CSPP1, encoding a core centrosomal protein, cause a range of ciliopathy phenotypes in humans.	43
24360807	2014	Mutations in CSPP1 lead to classical Joubert syndrome.	41
24360808	2014	Mutations in CSPP1 cause primary cilia abnormalities and Joubert syndrome with or without Jeune asphyxiating thoracic dystrophy.	69

Citation

Dessen P

CSPP1 (centrosome and spindle pole associated protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2015-02-01

Online version: http://atlasgeneticsoncology.org/gene/55031/cspp1-(centrosome-and-spindle-pole-associated-protein-1)