STRA6 (signaling receptor and transporter of retinol STRA6)

2015-02-01  

Identity

HGNC
LOCATION
15q24.1
LOCUSID
ALIAS
MCOPCB8,MCOPS9,PP14296
FUSION GENES

Other Information

Locus ID:

NCBI: 64220
MIM: 610745
HGNC: 30650
Ensembl: ENSG00000137868

Variants:

dbSNP: 64220
ClinVar: 64220
TCGA: ENSG00000137868
COSMIC: STRA6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000137868ENST00000323940Q9BX79
ENSG00000137868ENST00000395105Q9BX79
ENSG00000137868ENST00000416286J3KQI6
ENSG00000137868ENST00000423167Q9BX79
ENSG00000137868ENST00000432245Q9BX79
ENSG00000137868ENST00000449139Q9BX79
ENSG00000137868ENST00000535552Q9BX79
ENSG00000137868ENST00000563965Q9BX79
ENSG00000137868ENST00000569936I3NI08
ENSG00000137868ENST00000571341I3L0M6
ENSG00000137868ENST00000572785I3L2B6
ENSG00000137868ENST00000573391I3L1C7
ENSG00000137868ENST00000574278Q9BX79
ENSG00000137868ENST00000616000Q9BX79

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
DiseaseREACTOMER-HSA-1643685
Diseases of signal transductionREACTOMER-HSA-5663202
Diseases associated with visual transductionREACTOMER-HSA-2474795
Retinoid cycle disease eventsREACTOMER-HSA-2453864
Signal TransductionREACTOMER-HSA-162582
Visual phototransductionREACTOMER-HSA-2187338
The canonical retinoid cycle in rods (twilight vision)REACTOMER-HSA-2453902

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
366354822023STRA6 is essential for induction of vascular smooth muscle lineages in human embryonic cardiac outflow tract development.3
367584162023Up-regulation of STRA6 predicts poor prognosis and contributes to oxaliplatin resistance in colorectal cancer.2
368435932023STRA6 regulates tumor immune microenvironment and is a prognostic marker in BRAF-mutant papillary thyroid carcinoma.2
366354822023STRA6 is essential for induction of vascular smooth muscle lineages in human embryonic cardiac outflow tract development.3
367584162023Up-regulation of STRA6 predicts poor prognosis and contributes to oxaliplatin resistance in colorectal cancer.2
368435932023STRA6 regulates tumor immune microenvironment and is a prognostic marker in BRAF-mutant papillary thyroid carcinoma.2
315970152020Electronegative low-density lipoprotein of patients with metabolic syndrome induces pathogenesis of aorta through disruption of the stimulated by retinoic acid 6 cascade.4
328596292020STRA6 Expression Serves as a Prognostic Biomarker of Gastric Cancer.4
315970152020Electronegative low-density lipoprotein of patients with metabolic syndrome induces pathogenesis of aorta through disruption of the stimulated by retinoic acid 6 cascade.4
328596292020STRA6 Expression Serves as a Prognostic Biomarker of Gastric Cancer.4
308827002019Association of polymorphisms in STRA6 gene with gestational diabetes mellitus in a Chinese Han population.4
309868212019The protective variant rs7173049 at LOXL1 locus impacts on retinoic acid signaling pathway in pseudoexfoliation syndrome.10
316947212019STRA6 exerts oncogenic role in gastric tumorigenesis by acting as a crucial target of miR-873.19
308827002019Association of polymorphisms in STRA6 gene with gestational diabetes mellitus in a Chinese Han population.4
309868212019The protective variant rs7173049 at LOXL1 locus impacts on retinoic acid signaling pathway in pseudoexfoliation syndrome.10

Citation

Dessen P

STRA6 (signaling receptor and transporter of retinol STRA6)

Atlas Genet Cytogenet Oncol Haematol. 2015-02-01

Online version: http://atlasgeneticsoncology.org/gene/55034/stra6-(signaling-receptor-and-transporter-of-retinol-stra6)