Identity
HGNC
LOCATION
6q23.2
LOCUSID
ALIAS
MGC:8389,MGC:9620,STUD,TLF,TLP,TRF2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9519
MIM: 605521
HGNC: 11589
Ensembl: ENSG00000028839
Variants:
dbSNP: 9519
ClinVar: 9519
TCGA: ENSG00000028839
COSMIC: TBPL1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 28082682 | 2017 | TBP-like Protein (TLP) Disrupts the p53-MDM2 Interaction and Induces Long-lasting p53 Activation. | 4 |
| 28082682 | 2017 | TBP-like Protein (TLP) Disrupts the p53-MDM2 Interaction and Induces Long-lasting p53 Activation. | 4 |
| 27696626 | 2016 | Ubiquitin-proteasome-dependent degradation of TBP-like protein is prevented by direct binding of TFIIA. | 0 |
| 27696626 | 2016 | Ubiquitin-proteasome-dependent degradation of TBP-like protein is prevented by direct binding of TFIIA. | 0 |
| 26398009 | 2015 | Tumor suppressor microRNA-18a regulates tumor proliferation and invasion by targeting TBPL1 in colorectal cancer cells. | 10 |
| 26398009 | 2015 | Tumor suppressor microRNA-18a regulates tumor proliferation and invasion by targeting TBPL1 in colorectal cancer cells. | 10 |
| 24594805 | 2014 | Interaction between transactivation domain of p53 and middle part of TBP-like protein (TLP) is involved in TLP-stimulated and p53-activated transcription from the p21 upstream promoter. | 4 |
| 24870791 | 2014 | MiR-133b acts as a tumor suppressor and negatively regulates TBPL1 in colorectal cancer cells. | 22 |
| 24594805 | 2014 | Interaction between transactivation domain of p53 and middle part of TBP-like protein (TLP) is involved in TLP-stimulated and p53-activated transcription from the p21 upstream promoter. | 4 |
| 24870791 | 2014 | MiR-133b acts as a tumor suppressor and negatively regulates TBPL1 in colorectal cancer cells. | 22 |
| 22511763 | 2012 | TATA-binding protein (TBP)-like protein is required for p53-dependent transcriptional activation of upstream promoter of p21Waf1/Cip1 gene. | 11 |
| 22511763 | 2012 | TATA-binding protein (TBP)-like protein is required for p53-dependent transcriptional activation of upstream promoter of p21Waf1/Cip1 gene. | 11 |
| 19369647 | 2009 | Identification of potentially damaging amino acid substitutions leading to human male infertility. | 8 |
| 19858204 | 2009 | TATA-binding Protein (TBP)-like Protein Is Engaged in Etoposide-induced Apoptosis through Transcriptional Activation of Human TAp63 Gene. | 11 |
| 19369647 | 2009 | Identification of potentially damaging amino acid substitutions leading to human male infertility. | 8 |
Citation
Dessen P
TBPL1 (TATA-box binding protein like 1)
Atlas Genet Cytogenet Oncol Haematol. 2015-02-01
Online version: http://atlasgeneticsoncology.org/gene/55048/tbpl1-(tata-box-binding-protein-like-1)
