Identity
HGNC
LOCATION
5q14.1
LOCUSID
ALIAS
HOMER,HOMER1A,HOMER1B,HOMER1C,SYN47,Ves-1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9456
MIM: 604798
HGNC: 17512
Ensembl: ENSG00000152413
Variants:
dbSNP: 9456
ClinVar: 9456
TCGA: ENSG00000152413
COSMIC: HOMER1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000152413 | ENST00000282260 | Q86YM7 |
| ENSG00000152413 | ENST00000334082 | Q86YM7 |
| ENSG00000152413 | ENST00000508576 | Q86YM7 |
| ENSG00000152413 | ENST00000535690 | Q86YM6 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA445254 | Parkinson Disease | Disease | ClinicalAnnotation | associated | PD | 24126708 | |
| PA449841 | haloperidol | Chemical | MultilinkAnnotation | associated | 27023437 | ||
| PA450213 | levodopa | Chemical | ClinicalAnnotation | associated | PD | 24126708 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36181383 | 2022 | CircHOMER1 aggravates oxidative stress, inflammation and extracellular matrix deposition in high glucose-induced human mesangial cells. | 1 |
| 36181383 | 2022 | CircHOMER1 aggravates oxidative stress, inflammation and extracellular matrix deposition in high glucose-induced human mesangial cells. | 1 |
| 33431662 | 2021 | Multiple signaling pathways are essential for synapse formation induced by synaptic adhesion molecules. | 20 |
| 34204449 | 2021 | The mTORC2 Regulator Homer1 Modulates Protein Levels and Sub-Cellular Localization of the CaSR in Osteoblast-Lineage Cells. | 4 |
| 34225586 | 2021 | The Role of Stress-Induced Changes of Homer1 Expression in Stress Susceptibility. | 0 |
| 34788607 | 2021 | Homer1a regulates Shank3 expression and underlies behavioral vulnerability to stress in a model of Phelan-McDermid syndrome. | 6 |
| 33431662 | 2021 | Multiple signaling pathways are essential for synapse formation induced by synaptic adhesion molecules. | 20 |
| 34204449 | 2021 | The mTORC2 Regulator Homer1 Modulates Protein Levels and Sub-Cellular Localization of the CaSR in Osteoblast-Lineage Cells. | 4 |
| 34225586 | 2021 | The Role of Stress-Induced Changes of Homer1 Expression in Stress Susceptibility. | 0 |
| 34788607 | 2021 | Homer1a regulates Shank3 expression and underlies behavioral vulnerability to stress in a model of Phelan-McDermid syndrome. | 6 |
| 32142100 | 2020 | Self-reported Sleep Problems Related to Amyloid Deposition in Cortical Regions with High HOMER1 Gene Expression. | 10 |
| 32645048 | 2020 | A single nucleotide polymorphism in the HOMER1 gene is associated with sleep latency and theta power in sleep electroencephalogram. | 2 |
| 32142100 | 2020 | Self-reported Sleep Problems Related to Amyloid Deposition in Cortical Regions with High HOMER1 Gene Expression. | 10 |
| 32645048 | 2020 | A single nucleotide polymorphism in the HOMER1 gene is associated with sleep latency and theta power in sleep electroencephalogram. | 2 |
| 31078268 | 2019 | Interaction of the Homer1 EVH1 domain and skeletal muscle ryanodine receptor. | 5 |
Citation
Dessen P
HOMER1 (homer scaffold protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2015-02-01
Online version: http://atlasgeneticsoncology.org/gene/55049/homer1-(homer-scaffold-protein-1)
