Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 181
MIM: 602311
HGNC: 330
Ensembl: ENSG00000159723
Variants:
dbSNP: 181
ClinVar: 181
TCGA: ENSG00000159723
COSMIC: AGRP
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000159723 | ENST00000290953 | O00253 |
| ENSG00000159723 | ENST00000290953 | C6SUN5 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Adipocytokine signaling pathway | KEGG | ko04920 |
| Adipocytokine signaling pathway | KEGG | hsa04920 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36577844 | 2023 | AgRP neurons coordinate the mitigation of activity-based anorexia. | 6 |
| 36765131 | 2023 | Nuclear receptor 5A2 regulation of Agrp underlies olanzapine-induced hyperphagia. | 0 |
| 36577844 | 2023 | AgRP neurons coordinate the mitigation of activity-based anorexia. | 6 |
| 36765131 | 2023 | Nuclear receptor 5A2 regulation of Agrp underlies olanzapine-induced hyperphagia. | 0 |
| 33470098 | 2021 | Discovery of Molecular Interactions of the Human Melanocortin-4 Receptor (hMC4R) Asp189 (D189) Amino Acid with the Endogenous G-Protein-Coupled Receptor (GPCR) Antagonist Agouti-Related Protein (AGRP) Provides Insights to AGRP's Inverse Agonist Pharmacology at the hMC4R. | 2 |
| 33470098 | 2021 | Discovery of Molecular Interactions of the Human Melanocortin-4 Receptor (hMC4R) Asp189 (D189) Amino Acid with the Endogenous G-Protein-Coupled Receptor (GPCR) Antagonist Agouti-Related Protein (AGRP) Provides Insights to AGRP's Inverse Agonist Pharmacology at the hMC4R. | 2 |
| 32414136 | 2020 | Mitochondrial Dynamics and Microglia as New Targets in Metabolism Regulation. | 12 |
| 32414136 | 2020 | Mitochondrial Dynamics and Microglia as New Targets in Metabolism Regulation. | 12 |
| 30597030 | 2019 | Plasma Agouti-Related Protein and Cortisol Levels in Cushing Disease: Evidence for the Regulation of Agouti-Related Protein by Glucocorticoids in Humans. | 7 |
| 31361303 | 2019 | Plasma Agouti-Related Protein Levels in Acromegaly and Effects of Surgical or Pegvisomant Therapy. | 5 |
| 30597030 | 2019 | Plasma Agouti-Related Protein and Cortisol Levels in Cushing Disease: Evidence for the Regulation of Agouti-Related Protein by Glucocorticoids in Humans. | 7 |
| 31361303 | 2019 | Plasma Agouti-Related Protein Levels in Acromegaly and Effects of Surgical or Pegvisomant Therapy. | 5 |
| 28264929 | 2017 | The agouti-related peptide binds heparan sulfate through segments critical for its orexigenic effects. | 4 |
| 28264929 | 2017 | The agouti-related peptide binds heparan sulfate through segments critical for its orexigenic effects. | 4 |
| 26226973 | 2016 | Analysis of MC4R rs17782313, POMC rs1042571, APOE-Hha1 and AGRP rs3412352 genetic variants with susceptibility to obesity risk in North Indians. | 5 |
Citation
Dessen P
AGRP (agouti related neuropeptide)
Atlas Genet Cytogenet Oncol Haematol. 2015-02-01
Online version: http://atlasgeneticsoncology.org/gene/55051/agrp-(agouti-related-neuropeptide)
