PWWP2A (PWWP domain containing 2A)

2014-11-01  

Identity

HGNC
PWWP2A
LOCATION
5q33.3
LOCUSID
114825
ALIAS
MST101
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 114825
MIM: 617823
HGNC: 29406
Ensembl: ENSG00000170234

Variants:

dbSNP: 114825
ClinVar: 114825
TCGA: ENSG00000170234
COSMIC: PWWP2A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000170234ENST00000307063Q96N64
ENSG00000170234ENST00000456329Q96N64
ENSG00000170234ENST00000520662H0YC08
ENSG00000170234ENST00000521424H0YC06
ENSG00000170234ENST00000523662Q96N64
ENSG00000170234ENST00000524050H0YB44

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
313769352019Dysregulation of cPWWP2A-miR-579 axis mediates dexamethasone-induced cytotoxicity in human osteoblasts.8
313769352019Dysregulation of cPWWP2A-miR-579 axis mediates dexamethasone-induced cytotoxicity in human osteoblasts.8
302282602018A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes.24
303274632018PWWP2A binds distinct chromatin moieties and interacts with an MTA1-specific core NuRD complex.26
302282602018A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes.24
303274632018PWWP2A binds distinct chromatin moieties and interacts with an MTA1-specific core NuRD complex.26
286459172017Multivalent binding of PWWP2A to H2A.Z regulates mitosis and neural crest differentiation.27
286459172017Multivalent binding of PWWP2A to H2A.Z regulates mitosis and neural crest differentiation.27

Citation

Dessen P

PWWP2A (PWWP domain containing 2A)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/55062/pwwp2a-(pwwp-domain-containing-2a)